bs-19685P

bs-19685P

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  • 2025年10月15日
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      500ug

    产品编号bs-19685P
    英文名称PURA Antibody Blocking Peptide
    中文名称富含嘌呤元件结合蛋白A封闭多肽
    英文别名PUR ALPHA; PUR1; purA; PURA_HUMAN; PURALPHA; Purine rich element binding protein A; Purine rich single stranded DNA binding protein alpha; Purine-rich single-stranded DNA-binding protein alpha; Transcriptional activator protein PUR alpha; Transcriptional activator protein Pur-alpha.
    纯化方法HPLC
    研究领域

    Epigenetics and Nuclear Signaling > Chromatin Binding Proteins > DNA / RNA binding

    Epigenetics and Nuclear Signaling > Chromosome Structure > Telomeres

    Epigenetics and Nuclear Signaling > DNA / RNA > DNA Synthesis

    Epigenetics and Nuclear Signaling > Transcription > Preinitiation complex

    亚细胞定位Nucleus.
    相似性Belongs to the PUR DNA-binding protein family.
    功能This is a probable transcription activator that specifically binds the purine-rich single strand of the PUR element located upstream of the MYC gene. May play a role in the initiation of DNA replication and in recombination.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. [provided by RefSeq, Jul 2008]

     

     

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