bs-6579P

bs-6579P

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  • 2025年10月15日
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      500ug

    产品编号bs-6579P
    英文名称GH1 Antibody Blocking Peptide
    中文名称生长激素封闭多肽
    英文别名GH 1; GH; GH N; GH-N; GH1; GHN; Growth Hormone 1; Growth hormone 1 variant 1; Growth hormone 1 variant 2; Growth hormone; Growth Hormone Normal; Growth Hormone Pituitary; Growth hormone, normal; Growth hormone, pituitary; HG1; hGH N; hGH-N; HGHN; IGHD1B; Pituitary Growth Hormone; RNGHGP; SOMA_HUMAN; Somatotropin C; Somatotropin; Somatotropin I Precursor.
    纯化方法HPLC
    研究领域

    Developmental Biology > Post embryonic development > Growth hormones

    Signal Transduction > Growth Factors/Hormones > Hormones

    亚基Monomer, dimer, trimer, tetramer and pentamer, disulfide-linked or non-covalently associated, in homopolymeric and heteropolymeric combinations. Can also form a complex either with G‌‌HBP or with the alpha2-macroglobulin complex.
    亚细胞定位Secreted.
    相似性Belongs to the somatotropin/prolactin family.
    功能Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. [provided by RefSeq, Jul 2008]

     

     

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