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500ug
| 产品编号 | bs-1878P |
| 英文名称 | Rad52 Antibody Blocking Peptide |
| 中文名称 | Rad52封闭多肽 |
| 英文别名 | DNA repair protein RAD52; DNA repair protein RAD52 homolog; RAD 52; RAD52 homolog (S. cerevisiae); RAD52 homolog; Recombination protein RAD52; Rhabdomyosarcoma antigen MU RMS 40.23; DNA repair protein RAD52 homolog; RAD52_HUMAN; RAD52 homolog. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > DNA / RNA > DNA Damage & Repair > Homologous Recomb. |
| 亚基 | The full-length protein forms heptameric rings. Interacts with ABL1. |
| 亚细胞定位 | Nucleus (Potential). |
| 翻译后修饰 | Phosphorylated upon DNA damage by ABL1, and probably by ATM or ATR. |
| 相似性 | Belongs to the RAD52 family. |
| 功能 | Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. [provided by RefSeq, Jul 2008] |
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文献和实验花的横切面的平面图。如图所示，即对花叶在花轴上的排列位置，各花叶数及其互相的位置关系等可一目了然地表示出来。花图式是Turpin（ 1819）所创造，经 A． P． de Candolle等人的使用，而由 A． Eichler（ 1875— 1878）集其大成。花图式通常以有斜线的宽弧表示萼片，以黑色弧线表示花瓣，以花药的横切面示雄蕊，以子房的横切面示雌蕊。另外将花序轴放在后面的位置以示腋生花。花图式的缺点就是不能表示花叶的相对大小。
将在试管内受精（in vitro fertilizatio n）所得的人的早期胚胎，移于母体的子宫内，经过正常的妊娠过程产生的婴儿叫做试管婴儿。因在试管内发育只是从受精至卵裂期的很短一段时间，所以应称试管内受精儿或体外受精儿。哺乳类的试管内受精的最初尝试，是由S.L.Shenk（1878）用兔和土拨鼠来进行的，并观察了极体的出现和卵裂。M.C.Chang（1959）曾报道将由试管内受精得到的兔胚移植于子宫内，产出了幼兔。70年代初相继报道了用大白鼠及小白鼠作了同样的成功
deposit: NoPrice_code: AAvailability in cell line catalogues: ATCC CCL 61; IZSBS BS CL15; DSMZ ACC 110;Bibliographic references:J Exp Med 1958;108:945 Proc Nat Acad Sci USA 1968;60:1275CHO-K1 (hamster, Chinese, ovary)Morphology: epithelial-likeSpecies
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