- ￥2800
- Proteintech
- CL750-82946
- 2025年10月09日
- WB, FC (Intra)
- Rabbit
- human
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- 详细信息
- 技术资料
- 免疫原：
Recombinant human LAMB2 protein
- 亚型：
IgG
- 保存条件：
Store at -20°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性：
Recombinant
- 标记物：
CoraLite® Plus 750 Fluorescent Dye
- 适应物种：
human
- 宿主：
Rabbit
- 应用范围：
WB, FC (Intra)
- 靶点：
LAMB2
- 抗体英文名：
CoraLite® Plus 750-conjugated LAMB2 Recombinant monoclonal antibody
- 抗体名：
CoraLite® Plus 750-conjugated LAMB2 Recombinant monoclonal antibody
- 规格：
100ul
经过测试的应用
| Positive WB detected in | HeLa cells |
| Positive FC (Intra) detected in | HepG2 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:8000 |
| Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.25 ug per 10^6 cells in a 100 µl suspension |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL750-82946 targets LAMB2 in WB, FC (Intra) applications and shows reactivity with human samples.
| 经测试应用 | WB, FC (Intra) |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag33468 Product name: Recombinant human LAMB2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1549-1798 aa of NM_002292.3 Sequence: AEQIQHLAGAIAERVRSLADVDAILARTVGDVRRAEQLLQDARRARSWAEDEKQKAETVQAALEEAQRAQGIAQGAIRGAVADTRDTEQTLYQVQERMAGAERALSSAGERARQLDALLEALKLKRAGNSLAASTAEETAGSAQGRAQEAEQLLRGPLGDQYQTVKALAERKAQGVLAAQARAEQLRDEARDLLQAAQDKLQRLQELEGTYEENERALESKAAQLDGLEARMRSVLQAINLQVQIYNTCQ |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | laminin, beta 2 (laminin S) |
| 别名 | LAMS, Laminin 3 subunit beta, Laminin 15 subunit beta, Laminin 14 subunit beta, Laminin 11 subunit beta |
| 计算分子量 | 196 kDa |
| 观测分子量 | 195-200 kDa |
| GenBank蛋白编号 | NM_002292.3 |
| 基因名称 | LAMB2 |
| Gene ID (NCBI) | 3913 |
| RRID | AB_3673749 |
| 偶联类型 | CoraLite® Plus 750 Fluorescent Dye |
| 最大激发/发射波长 | 755 nm / 780 nm |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P55268 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
LAMB2 (laminin subunit beta 2), also known as LAMS. Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins, composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively), form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. This gene encodes the beta chain isoform laminin, beta 2. It is enriched in the basement membrane of muscles at the neuromuscular junctions, kidney glomerulus and vascular smooth muscle. Transgenic mice in which the beta 2 chain gene was inactivated by homologous recombination, showed defects in the maturation of neuromuscular junctions and impairment of glomerular filtration. The calculated molecular weight of LAMB2 is 200 kDa.
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