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CoraLite® Plus 488 Anti-Human

CD62L (DREG56) CL488-65167
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  • ¥920 - 2310
  • Proteintech已认证
  • CL488-65167
  • 2025年10月09日
  • FC
  • Mouse
  • Human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 亚型

      IgG1, kappa

    • 保存条件

      Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

    • 克隆性

      Monoclonal

    • 标记物

      CoraLite® Plus 488 Fluorescent Dye

    • 适应物种

      Human

    • 宿主

      Mouse

    • 应用范围

      FC

    • 靶点

      CD62L

    • 抗体英文名

      CoraLite® Plus 488 Anti-Human CD62L (DREG56)

    • 抗体名

      CoraLite® Plus 488 Anti-Human CD62L (DREG56)

    • 规格

      25tests/100tests

    规格:25tests产品价格:¥920.0
    规格:100tests产品价格:¥2310.0

    经过测试的应用

    Positive FC detected inhuman PBMCs
    For other applications, we recommend the unconjugated version of this antibody, 65167-1-Ig

    推荐稀释比

    应用推荐稀释比
    Flow Cytometry (FC)FC : 5 ul per 10^6 cells in 100 μl suspension
    This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
    Sample-dependent, Check data in validation data gallery.

    产品信息

    CL488-65167 targets CD62L in FC applications and shows reactivity with Human samples.

    经测试应用 FC
    经测试反应性 Human
    免疫原

    fusion protein

    宿主/亚型 Mouse / IgG1, kappa
    抗体类别 Monoclonal
    产品类型 Antibody
    全称 selectin L
    别名 CD62L, gp90 MEL, hLHRc, L selectin, LAM 1, LAM1, LECAM1, Leu 8, Leukocyte adhesion molecule 1, LNHR, LSEL, Lyam 1, LYAM1, Lymph node homing receptor, PLNHR, selectin L, SELL, TQ1
    计算分子量 42 kDa
    GenBank蛋白编号BC020758
    基因名称 CD62L
    Gene ID (NCBI) 6402
    ENSEMBL Gene IDENSG00000188404
    RRIDAB_3084156
    偶联类型 CoraLite® Plus 488 Fluorescent Dye
    最大激发/发射波长493 nm / 522 nm
    形式Liquid
    纯化方式Purified by protein-A affinity chromatography
    UNIPROT IDP14151
    储存缓冲液 PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3.
    储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

    背景介绍

    CD62L, also known as L-selectin or SELL, is a member of the selectin family of adhesion molecules that also include CD62E (E-selectin) and CD62P (P-selectin) (PMID: 2663882, 2473156, 1382078). CD62L is a highly glycosylated protein of 95-105 kDa on neutrophils and 74 kDa on lymphocytes (PMID: 1382078; 1694883, 1695155). CD62L is expressed on the surface of most leukocytes, including lymphocytes, neutrophils, monocytes, eosinophils, hematopoietic progenitor cells, and immature thymocytes (PMID: 1694883, 1688580). It mediates the binding of lymphocytes to high endothelial venules (HEV) of peripheral lymph nodes through interactions with a constitutively expressed ligand, and is also involved in lymphocyte, neutrophil, and monocyte attachment to endothelium at sites of inflammation (PMID: 1382078).

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