KLHDC3 重组单克隆抗体  84217-4-RR

KLHDC3 重组单克隆抗体 84217-4-RR

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  • ¥1500 - 3280
  • Proteintech已认证
  • 84217-4-RR
  • 2025年10月09日
  • WB, FC (Intra), ELISA
  • Rabbit
  • human, rat
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    • 详细信息
    • 技术资料
    • 免疫原

      Recombinant human KLHDC3 protein

    • 亚型

      IgG

    • 保存条件

      Store at -20°C. Stable for one year after shipment.

    • 克隆性

      Recombinant

    • 标记物

      Unconjugated

    • 适应物种

      human, rat

    • 宿主

      Rabbit

    • 应用范围

      WB, FC (Intra), ELISA

    • 靶点

      KLHDC3

    • 抗体英文名

      KLHDC3 Recombinant monoclonal antibody

    • 抗体名

      KLHDC3 Recombinant monoclonal antibody

    • 规格

      50ul/100ul/150ul

    规格:50ul产品价格:¥1500.0
    规格:100ul产品价格:¥2480.0
    规格:150ul产品价格:¥3280.0

    经过测试的应用

    Positive WB detected inNCI-H1299 cells, PC-3 cells, HepG2 cells, K-562 cells, HEK-293T cells, rat testis tissue
    Positive FC (Intra) detected inPC-3 cells, U-251 cells

    推荐稀释比

    应用推荐稀释比
    Western Blot (WB)WB : 1:5000-1:50000
    Flow Cytometry (FC) (INTRA)FC (INTRA) : 0.25 ug per 10^6 cells in a 100 µl suspension
    It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
    Sample-dependent, Check data in validation data gallery.

    产品信息

    84217-4-RR targets KLHDC3 in WB, FC (Intra), ELISA applications and shows reactivity with human, rat samples.

    经测试应用 WB, FC (Intra), ELISA
    经测试反应性 human, rat
    免疫原

    CatNo: Ag4879

    Product name: Recombinant human KLHDC3 protein

    Source: e coli.-derived, PGEX-4T

    Tag: GST

    Domain: 1-248 aa of BC041793

    Sequence: MTPKGPAMCSMPLTSADCFSNDIHKLDTSTMTWTLICTKGSPARWRDFHSATMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLDCPPTPVLPEGRRSHSAFGYNGELYIFGGYNARLNWHFHDLWKFNPVSFTWKKIEPKGKGPCPRRRQCCCIVGDKIVLFGGTSPSPEEGLGDEFDLIDHSDLHILDFSPSLKTLCKLAVIQYNLDQSCLPHDIRWELNAMTTNSNISRPIVSSHG

    宿主/亚型 Rabbit / IgG
    抗体类别 Recombinant
    产品类型 Antibody
    全称 kelch domain containing 3
    别名 PEAS, Kelch domain-containing protein 3, hPEAS, 241475G5
    计算分子量 382 aa, 43 kDa
    观测分子量43 kDa
    GenBank蛋白编号BC041793
    基因名称 KLHDC3
    Gene ID (NCBI) 116138
    RRIDAB_3671773
    偶联类型 Unconjugated
    形式Liquid
    纯化方式Protein A purification
    UNIPROT IDQ9BQ90
    储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
    储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

    背景介绍

    The Kelch domain-containing protein 3 (KLHDC3), also designated PEAS, contains 5 Kelch repeats and may be involved in meiotic recombination process. The gene encoding KLHDC3 maps to chromosome 6, which contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. KLHDC3 protein is mainly expressed in cytoplasm, also found in meiotic chromatin.

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