- ￥3200
- Proteintech
- CL647-13220
- 2025年10月09日
- FC (Intra)
- Rabbit
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant human GBP5 protein
- 亚型：
IgG
- 保存条件：
Store at -20°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性：
Polyclonal
- 标记物：
CoraLite® Plus 647 Fluorescent Dye
- 适应物种：
human
- 宿主：
Rabbit
- 应用范围：
FC (Intra)
- 靶点：
GBP5
- 抗体英文名：
CoraLite® Plus 647-conjugated GBP5 Polyclonal antibody
- 抗体名：
CoraLite® Plus 647-conjugated GBP5 Polyclonal antibody
- 规格：
100ul
经过测试的应用
| Positive FC (Intra) detected in | MCF-7 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.40 ug per 10^6 cells in a 100 µl suspension |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL647-13220 targets GBP5 in WB, IF, FC (Intra) applications and shows reactivity with human samples.
| 经测试应用 | FC (Intra) |
| 文献引用应用 | WB, IF |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag4103 Product name: Recombinant human GBP5 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 382-586 aa of BC031639 Sequence: LETLLDAKQNDICKRNLEASSDYCSALLKDIFGPLEEAVKQGIYSKPGGHNLFIQKTEELKAKYYREPRKGIQAEEVLQKYLKSKESVSHAILQTDQALTETEKKKKEAQVKAEAEKAEAQRLAAIQRQNEQMMQERERLHQEQVRQMEIAKQNWLAEQQKMQEQQMQEQAAQLSTTFQAQNRSLLSELQHAQRTVNNDDPCVLL |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | guanylate binding protein 5 |
| 别名 | Guanylate-binding protein 5, Guanine nucleotide-binding protein 5, GTP-binding protein 5, GBP-TA antigen, GBP-5 |
| 计算分子量 | 586 aa, 67 kDa |
| 观测分子量 | 65 kDa, 55 kDa |
| GenBank蛋白编号 | BC031639 |
| 基因名称 | GBP5 |
| Gene ID (NCBI) | 115362 |
| RRID | AB_2934881 |
| 偶联类型 | CoraLite® Plus 647 Fluorescent Dye |
| 最大激发/发射波长 | 654 nm / 674 nm |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q96PP8 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Guanylate binding protein (GBP) 5 belongs to the GBP family, which is involved in important cellular processes, including signal transduction, translation, vesicle trafficking, and exocytosis. GBP5 was reported to be a critical cellular factor in inflammasome assembly. Furthermore, GBP5 has been reported to induce inflammatory cytokines, including IL-1 beta and IL-18, through the activation of NLRP3 and AIM2. GBP5 encodes two isoforms: GBP-5a/b (67 kDa) and GBP-5ta (55 kDa)
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文献和实验| Species | Application | Title |
|---|---|---|
| WB,IF | Ecotoxicol Environ Saf Treatment of silicosis with quercetin depolarizing macrophages via inhibition of mitochondrial damage-associated pyroptosisAuthors - Chuan-Yong Xiao |
'）2 Fragment（Alexa Fluor® 555 Conjugate）#4413 Anti-Rabbit IgG（H+L）， F（ab'）2 Fragment（Alexa Fluor® 647 Conjugate）#4414 抗小鼠： Anti-Mouse IgG（H+L）， F（ab'）2 Fragment（Alexa Fluor® 488 Conjugate）#4408 Anti-Mouse IgG（H+L）， F（ab'）2 Fragment（Alexa Fluor
647 34079 SuperSignalâ West Pico Chemiluminescent Substrate Trial Kit 50
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