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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant human ADC protein
- 亚型:
IgG1
- 保存条件:
Store at -20°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性:
Monoclonal
- 标记物:
CoraLite®594 Fluorescent Dye
- 适应物种:
Human, mouse, pig, rat
- 宿主:
Mouse
- 应用范围:
IF/ICC, FC (Intra)
- 靶点:
ADC
- 抗体英文名:
CoraLite®594-conjugated ADC Monoclonal antibody
- 抗体名:
CoraLite®594-conjugated ADC Monoclonal antibody
- 规格:
100ul
经过测试的应用
| Positive IF/ICC detected in | A431 cells |
| Positive FC (Intra) detected in | A431 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.40 ug per 10^6 cells in a 100 µl suspension |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL594-67884 targets ADC in IF/ICC, FC (Intra) applications and shows reactivity with Human, mouse, pig, rat samples.
| 经测试应用 | IF/ICC, FC (Intra) |
| 经测试反应性 | Human, mouse, pig, rat |
| 免疫原 |
CatNo: Ag31049 Product name: Recombinant human ADC protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 251-460 aa of BC028128 Sequence: EIASVINSALDLYFPEGCGVDIFAELGRYYVTSAFTVAVSIIAKKEVLLDQPGREEENGSTSKTIVYHLDEGVYGIFNSVLFDNICPTPILQKKPSTEQPLYSSSLWGPAVDGCDCVAEGLWLPQLHVGDWLVFDNMGAYTVGMGSPFWGTQACHITYAMSRVAWEALRRQLMAAEQEDDVEGVCKPLSCGWEITDTLCVGPVFTPASIM |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | arginine decarboxylase |
| 别名 | AZIN2, AzI2, Arginine decarboxylase, ARGDC, Antizyme inhibitor 2 |
| 计算分子量 | 460 aa, 50 kDa |
| 观测分子量 | 48-50 kDa |
| GenBank蛋白编号 | BC028128 |
| 基因名称 | ADC |
| Gene ID (NCBI) | 113451 |
| RRID | AB_2934784 |
| 偶联类型 | CoraLite®594 Fluorescent Dye |
| 最大激发/发射波长 | 588 nm / 604 nm |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | Q96A70 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Antizyme inhibitor 2 (AZIN2) is a member of the antizyme inhibitor family, witch is able to bind to AZs and inhibit their action on both ODC activity and polyamine uptake. AZIN2 is predominantly expressed in the brain and testis and localized in the endoplasmic reticulum-golgi intermediate compartment. Available data suggest its role in cell growth, spermiogenesis, vesicular trafficking and secretion. Accumulation of azin2 has also been observed in brains of patients with Alzheimer's disease (PMID: 19832840) . AZIN2 has 5 described insoforms produced by alternative splicing. The molecular weight of AZIN2 is about 50 kDa.
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