- ￥5800
- Proteintech
- 66112-1-PBS
- 2026年05月29日
- WB, IHC, IF/ICC, Indirect ELISA
- Mouse
- human, mouse, rat, pig
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- 详细信息
- 技术资料
- 免疫原：
Recombinant human IDS protein
- 亚型：
IgG1
- 保存条件：
Store at -80°C.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
human, mouse, rat, pig
- 宿主：
Mouse
- 应用范围：
WB, IHC, IF/ICC, Indirect ELISA
- 靶点：
Iduronate 2 sulfatase
- 抗体英文名：
Iduronate 2 sulfatase Monoclonal antibody, PBS Only
- 抗体名：
Iduronate 2 sulfatase Monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
66112-1-PBS targets Iduronate 2 sulfatase in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig samples.
| 经测试应用 | WB, IHC, IF/ICC, Indirect ELISA |
| 经测试反应性 | human, mouse, rat, pig |
| 免疫原 |
CatNo: Ag19095 Product name: Recombinant human IDS protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-312 aa of BC006170 Sequence: MPPPRTGRGLLWLGLVLSSVCVALGSETQANSTTDALNVLLIIVDDLRPSLGCYGDKLVRSPNIDQLASHSLLFQNAFAQQAVCAPSRVSFLTGRRPDTTRLYDFNSYWRVHAGNFSTIPQYFKENGYVTMSVGKVFHPGISSNHTDDSPYSWSFPPYHPSSEKYENTKTCRGPDGELHANLLCPVDVLDVPEGTLPDKQSTEQAIQLLEKMKTSASPFFLAVGYHKPHIPFRYPKEFQKLYPLENITLAPDPEVPDGLPPVAYNPWMDIRQREDVQALNISVPYGPIPVDFQEDQSSTGFRLKTSSTRKYK |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | iduronate 2-sulfatase |
| 别名 | IDS, 1A3F9, Alpha-L-iduronate sulfate sulfatase, EC:3.1.6.13, Iduronate 2-sulfatase |
| 计算分子量 | 312aa,35 kDa; 550aa,62 kDa |
| 观测分子量 | 76 kDa, 55 kDa |
| GenBank蛋白编号 | BC006170 |
| 基因名称 | IDS |
| Gene ID (NCBI) | 3423 |
| RRID | AB_2881511 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | P22304 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Iduronate 2-sulfatase (IDS) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations causing IDS deficiency in humans result in the lysosomal storage of these glycosaminoglycans and Hunter syndrome, an X chromosome-linked disease. IDS is synthesized as two precursor forms of 76 and 90 kDa that are converted, through a 62 kDa intermediate, to 55 and 45 kDa mature polypeptides due to an internal proteolytic cleavage (PMID: 10838181).
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