- ￥5800
- Proteintech
- 66096-1-PBS
- 2025年10月09日
- WB, IHC, IF/ICC, IP, Indirect ELISA
- Mouse
- human, mouse
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- 详细信息
- 技术资料
- 免疫原：
Recombinant human VIL1 protein
- 亚型：
IgG1
- 保存条件：
Store at -80°C.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
human, mouse
- 宿主：
Mouse
- 应用范围：
WB, IHC, IF/ICC, IP, Indirect ELISA
- 靶点：
Villin
- 抗体英文名：
Villin Monoclonal antibody, PBS Only
- 抗体名：
Villin Monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
66096-1-PBS targets Villin in WB, IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, IHC, IF/ICC, IP, Indirect ELISA |
| 经测试反应性 | human, mouse |
| 免疫原 |
CatNo: Ag9637 Product name: Recombinant human VIL1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-350 aa of BC017303 Sequence: MTKLSAQVKGSLNITTPGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASSLSYDIHYWIGQDSSLDEQGAAAIYTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETNSYDVQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAKEIRDQERGGRTYVGVVDGENELASPKLMEVMNHVLGKRRELKAAVPDTVVEPALKAALKLYHVSDSEGNLVVREVATRPLTQDLLSHEDCYILDQGGLKIYVWKGKKANEQEKKGAMSHALNFIKAKQYPPSTQVEVQNDGAESAVFQQLFQKWT |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | villin 1 |
| 别名 | VIL1, 2B7B9, D2S1471, VIL, villin 1 |
| 计算分子量 | 827aa,93 kDa; 826aa,93 kDa |
| 观测分子量 | 93-95 kDa |
| GenBank蛋白编号 | BC017303 |
| 基因名称 | Villin |
| Gene ID (NCBI) | 7429 |
| RRID | AB_2881495 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P09327 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Villin 1 (VIL1) is a 95-kDa F-actin bundling and severing protein and its expression is restricted to epithelial cells with a brush border, like epithelial cells of the intestinal mucosa, gall bladder, renal proximal tubules and ductuli efferentes of the testis. VIL1 has been reported to be an epithelial cell-specific anti-apoptotic protein, and to have an important function in regulating actin dynamics, cell morphology, epithelial-to-mesenchymal transitions, cell migration and cell survival. In addition, VIL1 is a useful diagnostic marker for of various cancer, like cervical and endometrial adenocarcinomas, renal cell carcinoma. VIL1 was recently identified as a novel biomarker predictive for postoperative recurrence and poorer prognosis of high serum AFP associated HCC.
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