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Mouse CD169 重组单克隆抗体, PBS Only

(Capture) 86605-1-PBS
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  • ¥5800
  • Proteintech已认证
  • 86605-1-PBS
  • 2025年10月09日
  • WB, Cytometric bead array, Indirect ELISA
  • Rabbit
  • mouse
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 亚型

      IgG

    • 保存条件

      Store at -80°C.

    • 克隆性

      Recombinant

    • 标记物

      Unconjugated

    • 适应物种

      mouse

    • 宿主

      Rabbit

    • 应用范围

      WB, Cytometric bead array, Indirect ELISA

    • 靶点

      CD169

    • 抗体英文名

      Mouse CD169 Recombinant monoclonal antibody, PBS Only (Capture)

    • 抗体名

      Mouse CD169 Recombinant monoclonal antibody, PBS Only (Capture)

    • 规格

      100ug

    产品信息

    86605-1-PBS targets CD169 as part of a matched antibody pair:

    MP02539-1: 86605-1-PBS capture and 86605-2-PBS detection (validated in Cytometric bead array)

    Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

    This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

    经测试应用 WB, Cytometric bead array, Indirect ELISA
    经测试反应性 mouse
    免疫原

    CatNo: Eg5002

    Product name: recombinant mouse Siglec1 protein

    Source: mammalian cells-derived, pHZ-KIsec-C-rFc

    Tag: C-rFc

    Domain: 20-510 aa of NP_035556

    Sequence: TWGVSSPKNVQGLSGSCLLIPCIFSYPADVPVSNGITAIWYYDYSGKRQVVIHSGDPKLVDKRFRGRAELMGNMDHKVCNLLLKDLKPEDSGTYNFRFEISDSNRWLDVKGTTVTVTTDPSPPTITIPEELREGMERNFNCSTPYLCLQEKQVSLQWRGQDPTHSVTSSFQSLEPTGVYHQTTLHMALSWQDHGRTLLCQFSLGAHSSRKEVYLQVPHAPKGVEILLSSSGRNILPGDPVTLTCRVNSSYPAVSAVQWARDGVNLGVTGHVLRLFSAAWNDSGAYTCQATNDMGSLVSSPLSLHVFMAEVKMNPAGPVLENETVTLLCSTPKEAPQELRYSWYKNHILLEDAHASTLHLPAVTRADTGFYFCEVQNAQGSERSSPLSVVVRYPPLTPDLTTFLETQAGLVGILHCSVVSEPLATVVLSHGGLTLASNSGENDFNPRFRISSAPNSLRLEIRDLQPADSGEYTCLAVNSLGNSTSSLDFYAN

    宿主/亚型 Rabbit / IgG
    抗体类别 Recombinant
    产品类型 Antibody
    全称 sialic acid binding Ig-like lectin 1, sialoadhesin
    别名 Sa, SER, Sheep erythrocyte receptor, Sialic acid-binding Ig-like lectin 1, Sialoadhesin
    计算分子量183 kDa
    观测分子量220 kDa
    GenBank蛋白编号NP_035556
    基因名称 Siglec1
    Gene ID (NCBI) 20612
    偶联类型 Unconjugated
    形式Liquid
    纯化方式Protein A purification
    UNIPROT IDQ62230-1
    储存缓冲液 PBS only, pH 7.3.
    储存条件Store at -80°C.
    The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

    背景介绍

    CD169, also known as sheep erythrocyte receptor (SER), Sialoadhesin (Sn) or Siglec-1, is a sialic acid-binding immunoglobulin-like lectin that belongs to the SIGLEC family of the Ig superfamily (PMID: 3783087; 11133773). CD169 is a single-pass transmembrane protein containing a long extracellular domain, a transmembrane region, and a short cytoplasmic tail (PMID: 11133773). It is primarily expressed on the surface of specific macrophage subsets and its precursor monocytes, as well as on some DCs (PMID: 33408860). CD169 binds to sialic acid-containing glycoconjugates, particularly those with α(2,3)-linkages. It is involved in immune regulation, pathogen recognition, and cell-cell interactions.

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    图标文献和实验
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