- ￥5800
- Proteintech
- 82981-1-PBS
- 2025年10月09日
- IHC, FC (Intra), Indirect ELISA
- Rabbit
- human
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- 详细信息
- 技术资料
- 免疫原：
Recombinant human OGDHL protein
- 亚型：
IgG
- 保存条件：
Store at -80°C.
- 克隆性：
Recombinant
- 标记物：
Unconjugated
- 适应物种：
human
- 宿主：
Rabbit
- 应用范围：
IHC, FC (Intra), Indirect ELISA
- 靶点：
OGDHL
- 抗体英文名：
OGDHL Recombinant monoclonal antibody, PBS Only
- 抗体名：
OGDHL Recombinant monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
82981-1-PBS targets OGDHL in IHC, FC (Intra), Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | IHC, FC (Intra), Indirect ELISA |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag10794 Product name: Recombinant human OGDHL protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 661-1010 aa of BC026320 Sequence: SGQDVERGTFSHRHHVLHDQEVDRRTCVPMNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFISTGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDAYPAFTKDFEVSQLYDCNWIVVNCSTPANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSSFDQMVSGTSFQRVIPEDGAAARAPEQVQRLIFCTGKVYYDLVKERSSQDLEEKVAITRLEQISPFPFDLIKQEAEKYPGAELAWCQEEHKNMGYYDYISPRFMTILRRARPIWYVGRDPAAAPATGNRNTHLVSLKKFLDTAFNLQAFEGKTF |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | oxoglutarate dehydrogenase-like |
| 别名 | 230228B2, 2-oxoglutarate dehydrogenase complex component E1-like, 2-oxoglutarate dehydrogenase-like, mitochondrial, Alpha-ketoglutarate dehydrogenase-like, EC:1.2.4.2 |
| 计算分子量 | 1010 aa, 115 kDa |
| GenBank蛋白编号 | BC026320 |
| 基因名称 | OGDHL |
| Gene ID (NCBI) | 55753 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q9ULD0 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
OGDHL(oxoglutarate dehydrogenase-like) is also named as KGDE1KL, FLJ10851, KIAA1290 and belongs to the alpha-ketoglutarate dehydrogenase family. OGDHL is one of the rate-limiting component of the multienzyme OGDH complex (OGDHC) whose malfunction is associated with neuro-degeneration and it is localized only in the mitochondrial fraction and not in the cytosolic or nuclear fractions(PMID:23152800). OGDHL negatively regulates cell proliferation by inducing apoptosis in cervical cancer cells. It may thus participate in brain-specific control of 2-oxoglutarate distribution between energy production and synthesis of the neurotransmitter glutamate(PMID:18783430). It has 3 isoforms(114 kDa, 108 kDa, 91 kDa) produced by alternative splicing.
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