- ￥5800
- Proteintech
- 85961-1-PBS
- 2025年10月09日
- WB, Indirect ELISA
- Rabbit
- mouse, rat
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- 详细信息
- 技术资料
- 亚型：
IgG
- 保存条件：
Store at -80°C.
- 克隆性：
Recombinant
- 标记物：
Unconjugated
- 适应物种：
mouse, rat
- 宿主：
Rabbit
- 应用范围：
WB, Indirect ELISA
- 靶点：
IL-17RB
- 抗体英文名：
Mouse IL-17RB Recombinant monoclonal antibody, PBS Only
- 抗体名：
Mouse IL-17RB Recombinant monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
85961-1-PBS targets IL-17RB in WB, Indirect ELISA applications and shows reactivity with mouse, rat samples.
| 经测试应用 | WB, Indirect ELISA |
| 经测试反应性 | mouse, rat |
| 免疫原 |
CatNo: Eg2798 Product name: recombinant mouse Il17rb protein Source: mammalian cells-derived, V37 Tag: C-rFc Domain: 18-286 aa of NM_019583.3 Sequence: REPTIQCGSETGPSPEWMVQHTLTPGDLRDLQVELVKTSVAAEEFSILMNISWILRADASIRLLKATKICVSGKNNMNSYSCVRCNYTEAFQSQTRPSGGKWTFSYVGFPVELSTLYLISAHNIPNANMNEDSPSLSVNFTSPGCLNHVMKYKKQCTEAGSLWDPDITACKKNEKMVEVNFTTNPLGNRYTILIQRDTTLGFSRVLENKLMRTSVAIPVTEESEGAVVQLTPYLHTCGNDCIRREGTVVLCSETSAPIPPDDNRRMLGG |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | interleukin 17 receptor B |
| 别名 | Evi27, IL-17 receptor B, IL-17 receptor homolog 1, IL-17B receptor, Il17br |
| 计算分子量 | 56 kDa |
| 观测分子量 | 67 kDa |
| GenBank蛋白编号 | NM_019583.3 |
| 基因名称 | Il17rb |
| Gene ID (NCBI) | 50905 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q9JIP3-1 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
IL-17RB is a transmembrane protein that belongs to the IL-17 receptor family. IL-17RB has a SEFIR cytoplasmic domain implicated in homotypic dimerization and recruitment of signaling proteins (shared with IL-17RA) and a TRAF6-binding domain (not found in IL-17RA). IL-17RB is expressed in various endocrine tissues and epithelial cells in different organs such as kidney, liver, and mucosal tissues. The IL-17B/IL-17RB pathway is considered as a signaling cascade that promotes cancer cell survival, proliferation and migration. The pro-tumor functions associated with the IL 17B/IL-17RB pathway are diverse and complex because they involve mechanisms that act directly on tumor cells, and also indirect mechanisms that lead to tumor microenvironment remodeling.
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