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- 详细信息
- 技术资料
- 亚型:
IgG
- 保存条件:
Store at -80°C.
- 克隆性:
Recombinant
- 标记物:
Unconjugated
- 适应物种:
human
- 宿主:
Rabbit
- 应用范围:
FC
- 靶点:
CRTAM/CD355
- 抗体英文名:
Anti-Human CRTAM/CD355 Rabbit Recombinant Antibody, PBS Only
- 抗体名:
Anti-Human CRTAM/CD355 Rabbit Recombinant Antibody, PBS Only
- 规格:
500ug/1mg
| 规格: | 500ug | 产品价格: | ¥3600.0 |
|---|---|---|---|
| 规格: | 1mg | 产品价格: | ¥5000.0 |
产品信息
98157-1-PBS targets CRTAM/CD355 in FC applications and shows reactivity with human samples.
| 经测试应用 | FC |
| 经测试反应性 | human |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | cytotoxic and regulatory T cell molecule |
| 别名 | CRTAM, Cytotoxic and regulatory T-cell molecule, Class-I MHC-restricted T-cell-associated molecule, CD355, 241280B12 |
| 计算分子量 | 45 kDa |
| GenBank蛋白编号 | NM_019604.4 |
| 基因名称 | CRTAM |
| Gene ID (NCBI) | 56253 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purfication |
| UNIPROT ID | O95727-1 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Cytotoxic and regulatory T cell molecule (CRTAM, also known as CD355) is an immunoglobulin-superfamily transmembrane protein with V and C1-like Ig domains, which is involved in epithelial cell adhesion (PMID: 18329370; 20556794). CRTAM is critical to instruct the differentiation of CD4+ cytotoxic T cells (CTL) through the induction of eomesodermin and CTL-related genes (PMID: 26694968). It also regulates CD8+ T cell retention within the lymph node and eventually effector function (PMID: 19752223).
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