- ￥1500 - 3280
- Proteintech
- 84463-2-RR
- 2025年10月09日
- IF/ICC, ELISA
- Rabbit
- human
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
IgG
- 保存条件：
Store at -20°C. Stable for one year after shipment.
- 克隆性：
Recombinant
- 标记物：
Unconjugated
- 适应物种：
human
- 宿主：
Rabbit
- 应用范围：
IF/ICC, ELISA
- 靶点：
Integrin alpha 6
- 抗体英文名：
Integrin alpha 6 Recombinant monoclonal antibody
- 抗体名：
Integrin alpha 6 Recombinant monoclonal antibody
- 规格：
50ul/100ul/150ul
| 规格： | 50ul | 产品价格： | ￥1500.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥2480.0 |
| 规格： | 150ul | 产品价格： | ￥3280.0 |
经过测试的应用
| Positive IF/ICC detected in | A431 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
84463-2-RR targets Integrin alpha 6 in IF/ICC, ELISA applications and shows reactivity with human samples.
| 经测试应用 | IF/ICC, ELISA |
| 经测试反应性 | human |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | integrin, alpha 6 |
| 别名 | ITGA6, 241703E3, CD49 antigen-like family member F, CD49f, Integrin alpha-6 |
| 计算分子量 | 1073 aa, 119 kDa |
| GenBank蛋白编号 | BC136456 |
| 基因名称 | Integrin alpha 6 |
| Gene ID (NCBI) | 3655 |
| RRID | AB_3671984 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P23229 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
The integrins are a superfamily of cell adhesion receptors that bind to extracellular matrix ligands, cell-surface ligands, and soluble ligands (PMID: 17543136). They are transmembrane αβ heterodimers and at least 24 distinct integrin heterodimers are formed by the combination of 18 α and eight β known subunits (PMID: 17543136; 20029421). In addition to mediating cell adhesion, integrins also play important roles in modulating signal transduction pathways that control cellular responses including migration, proliferation, differentiation, and apoptosis (PMID:19118207). Integrin alpha 6 (ITGA6, also known as CD49f or VLA-6) is a 120-kDa single-pass type 1 transmembrane glycoprotein, which combines with the beta 1 subunit (ITGB1, CD29) or beta 4 subunit (ITGB4, CD104) to form heterodimeric laminin receptors (PMID: 1976638; 2351695). Integrin alpha 6 mediates cell-to-cell and cell-to-stroma adhesion. It has also been found in many different stem cell populations and is involved in homing and connecting stem cells to their niches and regulating self-renewal mechanisms in stem cells (PMID: 28494695).
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文献和实验associated alpha and beta subunits CD11a Aka alpha L; LFA-1 (in complex with CD18) An alpha integrin chain that binds to CD18 and mediates leukocyte adhesion and lymphocyte recirculation through lymph
CD51 分子 CD51 常用单克隆抗体或代号： 13C2,23C6,NK1- M7;(VNRa 链,integrin a V) 主要表达细胞： Pt,En,Meg [Pt] 分子质量(kDa)和结构： gp150,与CD61组成二聚体 功 能： 粘附VN、FN和vWF CD51 Aka vitronectin receptor-alpha chain; beta chain
CD49a/CD49b/CD49c/CD49d/CD49e/CD49f分子
键连接,与CD29组成VLA- 5 功 能： 粘附FN CD49f 常用单克隆抗体或代号： GOH3;(VAL- a 6,血小板gplc’) 主要表达细胞： Pt,Meg,Tsub [AS] 分子质量(kDa)和结构： gp150(120/30二硫键连接,与CD29组成VLA- 6 功 能： 粘附LM CD49a Aka very late antigen (VLA) alpha 1 chain, integrin alpha
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