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Anti-Human CD11c (BU15) Mouse

IgG2a Recombinant Antibody 65600-1-MR
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  • ¥600 - 3000
  • Proteintech已认证
  • 65600-1-MR
  • 2025年10月09日
  • FC
  • Mouse
  • Human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 亚型

      IgG2a

    • 保存条件

      Store at 2-8°C. Stable for one year after shipment.

    • 克隆性

      Recombinant

    • 标记物

      Unconjugated

    • 适应物种

      Human

    • 宿主

      Mouse

    • 应用范围

      FC

    • 靶点

      CD11c

    • 抗体英文名

      Anti-Human CD11c (BU15) Mouse IgG2a Recombinant Antibody

    • 抗体名

      Anti-Human CD11c (BU15) Mouse IgG2a Recombinant Antibody

    • 规格

      100ug/500ug/1mg

    规格:100ug产品价格:¥600.0
    规格:500ug产品价格:¥2200.0
    规格:1mg产品价格:¥3000.0

    经过测试的应用

    Positive FC detected inhuman peripheral blood leukocytes
    Planning an IHC experiment? We recommend our IHCeasy CD11c Ready-To-Use IHC Kit. CD11c primary antibody included.

    推荐稀释比

    应用推荐稀释比
    Flow Cytometry (FC)FC : 0.25 ug per 10^6 cells in 100 μl suspension
    This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
    Sample-dependent, Check data in validation data gallery.

    产品信息

    65600-1-MR targets CD11c in FC applications and shows reactivity with Human samples.

    经测试应用 FC
    经测试反应性 Human
    免疫原

    fusion protein

    宿主/亚型 Mouse / IgG2a
    抗体类别 Recombinant
    产品类型 Antibody
    全称 integrin, alpha X (complement component 3 receptor 4 subunit)
    别名 CD11C, Integrin alpha X, ITGAX, Leu M5, SLEB6
    计算分子量 1169 aa, 129 kDa
    GenBank蛋白编号BC038237
    基因名称 CD11c
    Gene ID (NCBI) 3687
    ENSEMBL Gene IDENSG00000140678
    RRIDAB_3670347
    偶联类型 Unconjugated
    形式Liquid
    纯化方式Protein A purification
    UNIPROT IDP20702
    储存缓冲液 PBS with 0.09% sodium azide, pH 7.3.
    储存条件Store at 2-8°C. Stable for one year after shipment.

    背景介绍

    Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11c, also known as integrin αX, is a type I transmembrane glycoprotein present on a variety of cells, including monocytes/macrophages, granulocytes, a subset of B cells, NK cells and dendritic cells (PMID: 2897326; 1680915; 1694698; 17389580). As a result of its high level of expression on most dendritic cells, CD11c is typically considered to be a marker of conventional dendritic cells (PMID: 27119555). CD11c forms an α/β heterodimer with CD18 (integrin β2). CD11c/CD18 acts as a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis (PMID: 1671533).

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    图标文献和实验
    相关实验
    • AbC Anti-Mouse Bead Kit

      suspension. 5)        Label another sample tube for each fluorochrome-conjugated antibody you are using, and add 1 drop of AbC™ capture beads (Component A in the AbC™ Anti-Mouse Bead Kit) to each tube. 6)        Add a pre-titrated

    • Protocol for anti-HA antibody Western Blotting

      seconds, and pour it off: this method was worked out in the Yamamoto lab eons ago). 7) Incubate with secondary antibody (anti-mouse) in 5% BSA/PBS/Tween as you would ordinarily. I usually go for 2 hours @ room temp. 8) 12-15 quick washes again(in 1XPBS

    • Technology and Production of Murine Monoclonal and Recombinant Antibodies and Antibody Fragments

      production described by K�hler and Milstein in 1975 (1 ). In the last 30 yr a number of genetically engineered antibody constructions have emerged, including chimeric and human-like antibodies as well as different antibody fragments. Nowadays, 18 rnAb

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