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- 详细信息
- 技术资料
- 免疫原:
Recombinant human USP48 protein
- 亚型:
IgG
- 保存条件:
Store at -80°C.
- 克隆性:
Recombinant
- 标记物:
Unconjugated
- 适应物种:
human
- 宿主:
Rabbit
- 应用范围:
WB, Indirect ELISA
- 靶点:
USP48
- 抗体英文名:
USP48 Recombinant monoclonal antibody, PBS Only
- 抗体名:
USP48 Recombinant monoclonal antibody, PBS Only
- 规格:
100ug
产品信息
86523-1-PBS targets USP48 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag2749 Product name: Recombinant human USP48 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 782-1035 aa of BC013567 Sequence: MFTFASMTKEDSKLIALIWPSEWQMIQKLFVVDHVIKITRIEVGDVNPSETQYISEPKLCPECREGLLCQQQRDLREYTQATIYVHKVVDNKKVMKDSAPELNVSSSETEEDKEEAKPDGEKDPDFNQSNGGTKRQKISHQNYIAYQKQVIRRSMRHRKVRGEKALLVSANQTLKELKIQIMHAFSVAPFDQNLSIDGKILSDDCATLGTLGVIPESVILLKADEPIADYAAMDDVMQVCMPEEGFKGTGLLGH |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | ubiquitin specific peptidase 48 |
| 别名 | Deubiquitinating enzyme 48, EC:3.4.19.12, RAP1GA1, Ubiquitin carboxyl-terminal hydrolase 48, Ubiquitin thiolesterase 48 |
| 计算分子量 | 1035 aa, 119 kDa |
| 观测分子量 | 120 kDa |
| GenBank蛋白编号 | BC013567 |
| 基因名称 | USP48 |
| Gene ID (NCBI) | 84196 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q86UV5 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
USP48 (Ubiquitin Specific Peptidase 48) is a deubiquitinating enzyme and a member of the Ubiquitin Specific Protease (USP) family. This protein specifically recognizes and cleaves ubiquitin chains on substrate proteins, reversing the ubiquitination process, thereby regulating the stability, activity, and subcellular localization of target proteins. USP48 plays a key role in various cellular processes, including DNA damage repair, cell cycle regulation, and gene transcription. Studies have shown that USP48 is closely related to pathological processes such as cancer and neurodegenerative diseases, for example, by stabilizing transcription factors or signaling pathway proteins to influence tumor development.
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