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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant mouse Tlr4 protein
- 亚型:
IgG
- 保存条件:
Store at 2-8°C. Stable for one year after shipment.
- 克隆性:
Recombinant
- 标记物:
Unconjugated
- 适应物种:
mouse
- 宿主:
Rabbit
- 应用范围:
FC
- 靶点:
TLR4/CD284
- 抗体英文名:
Anti-Mouse TLR4/CD284 Rabbit Recombinant Antibody
- 抗体名:
Anti-Mouse TLR4/CD284 Rabbit Recombinant Antibody
- 规格:
100ug/500ug/1mg
| 规格: | 100ug | 产品价格: | ¥600.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥2200.0 |
| 规格: | 1mg | 产品价格: | ¥3000.0 |
经过测试的应用
| Positive FC detected in | Balb/c mouse peritoneal macrophages |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 0.25 ug per 10^6 cells in 100 μl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
98018-1-RR targets TLR4/CD284 in WB, FC applications and shows reactivity with mouse samples.
| 经测试应用 | FC |
| 文献引用应用 | WB |
| 经测试反应性 | mouse |
| 文献引用反应性 | pig |
| 免疫原 |
CatNo: Ag32998 Product name: Recombinant mouse Tlr4 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 198-395 aa of NM_021297 Sequence: RENPQVNLSLDMSLNPIDFIQDQAFQGIKLHELTLRGNFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIMEGLCDVTIDEFRLTYTNDFSDDIVKFHCLANVSAMSLAGVSIKYLEDVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLTLTMNKGSISFKKVALPSLSYLDLSRNALSFSGCCSYSDLG |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | toll-like receptor 4 |
| 别名 | Tlr4, CD284, toll like receptor 4, 230463C7 |
| 计算分子量 | 96 kDa |
| GenBank蛋白编号 | NM_021297 |
| 基因名称 | Tlr4 |
| Gene ID (NCBI) | 21898 |
| RRID | AB_3672162 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purfication |
| UNIPROT ID | Q9QUK6 |
| 储存缓冲液 | PBS with 0.09% sodium azide, pH 7.3. |
| 储存条件 | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 interacts with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kB activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
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