- ￥5800
- Proteintech
- 68050-1-PBS
- 2025年10月09日
- WB, Indirect ELISA
- Mouse
- Human
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- 详细信息
- 技术资料
- 亚型：
IgG3
- 保存条件：
Store at -80°C.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human
- 宿主：
Mouse
- 应用范围：
WB, Indirect ELISA
- 靶点：
Phospho-MKK7 (Ser271/Thr275)
- 抗体英文名：
Phospho-MKK7 (Ser271/Thr275) Monoclonal antibody, PBS Only
- 抗体名：
Phospho-MKK7 (Ser271/Thr275) Monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
68050-1-PBS targets Phospho-MKK7 (Ser271/Thr275) in WB, Indirect ELISA applications and shows reactivity with Human samples.
| 经测试应用 | WB, Indirect ELISA |
| 经测试反应性 | Human |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Mouse / IgG3 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | mitogen-activated protein kinase kinase 7 |
| 别名 | JNK activating kinase 2, JNK kinase 2, JNKK 2, Jnkk2, MAP kinase kinase 7, MAP2K7, MAPK/ERK kinase 7, MAPKK 7, MAPKK7, MEK 7, MEK7, MKK7, Phospho-MKK7 (Ser271/Thr275), PRKMK7 |
| 计算分子量 | 47 kDa |
| 观测分子量 | 47-52 kDa |
| GenBank蛋白编号 | BC038295 |
| 基因名称 | MKK7 |
| Gene ID (NCBI) | 5609 |
| RRID | AB_2918792 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | O14733 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Dual specificity mitogen-activated protein kinase kinase 7 (MKK7), also known as MEK7 or MAP2K7, is a member of mitogen-activated kinase kinase (MAP2K) subfamily, and a key activator of c-Jun N-terminal kinase (JNK) signaling, a pathway that regulates primarily stress and inflammatory responses. MKK7 activity can be increased by either MKK7-autophosphorylation or phosphorylation of the Ser and Thr residues of the S-X-A-K-T motifs in the Kinase domain by upstream MEKK1, MEKK2, or MLK3.(PMID: 32783966, PMID: 31579105)
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