- ￥1350 - 3000
- Proteintech
- 68317-1-Ig
- 2025年10月09日
- WB, IF/ICC, ELISA
- Mouse
- Human, pig
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant human PBLD protein
- 亚型：
IgG1
- 保存条件：
Store at -20°C. Stable for one year after shipment.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human, pig
- 宿主：
Mouse
- 应用范围：
WB, IF/ICC, ELISA
- 靶点：
PBLD
- 抗体英文名：
PBLD Monoclonal antibody
- 抗体名：
PBLD Monoclonal antibody
- 规格：
50ul/100ul/150ul
| 规格： | 50ul | 产品价格： | ￥1350.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥2200.0 |
| 规格： | 150ul | 产品价格： | ￥3000.0 |
经过测试的应用
| Positive WB detected in | pig liver tissue, pig kidney tissue |
| Positive IF/ICC detected in | HEK-293 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:2000-1:10000 |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
68317-1-Ig targets PBLD in WB, IF/ICC, ELISA applications and shows reactivity with Human, pig samples.
| 经测试应用 | WB, IF/ICC, ELISA |
| 文献引用应用 | WB |
| 经测试反应性 | Human, pig |
| 文献引用反应性 | human, mouse |
| 免疫原 |
CatNo: Ag23827 Product name: Recombinant human PBLD protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-288 aa of BC009738 Sequence: MKLPIFIADAFTARAFRGNPAAVCLLENELDEDMHQKIAREMNLSETAFIRKLHPTDNFAQSSCFGLRWFTPASEVPLCGHATLASAAVLFHKIKNMNSTLTFVTLSGELRARRAEDGIVLDLPLYPAHPQDFHEVEDLIKTAIGNTLVQDICYSPDTQKLLVRLSDVYNRSFLENLKVNTENLLQVENTGKVKGLILTLKGEPGGQTQAFDFYSRYFAPWVGVAEDPVTGSAHAVLSSYWSQHLGKKEMHAFQCSHRGGELGISLRPDGRVDIRGGAAVVLEGTLTA |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | phenazine biosynthesis-like protein domain containing |
| 别名 | FLJ14767, FLJ35507, MAWBP, MAWD binding protein, MAWDBP, PBLD |
| 观测分子量 | 30 kDa |
| GenBank蛋白编号 | BC009738 |
| 基因名称 | PBLD |
| Gene ID (NCBI) | 64081 |
| RRID | AB_3085053 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | P30039 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
PBLD, also termed as MAWBP, was first identified from a human liver cDNA library using a yeast two-hybrid technique by Iriyama et al. As the only representative of phenazine biosynthesis-like protein family, PBLD is widely expressed in human tissues, such as brain, heart, lung, liver, pancreas, kidney, and placenta. Its expression is elevated in several diseases processes, including insulin resistance, folate deficiency, and hypotension. PBLD has been proved to be involved in gastric carcinogenesis, PBLD expression was attenuated in gastric cancer (GC) tissues, and negatively regulated the growth and invasion in gastric cancer cell-lines by inhibiting TGF-β1-induced EMT (Epithelial-Mesenchymal Transition).(PMID: 11355021, 17929853, 23687415, 26594798)
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文献和实验| Species | Application | Title |
|---|---|---|
| human | WB | Mol Cancer Discovery of vitexin as a novel VDR agonist that mitigates the transition from chronic intestinal inflammation to colorectal cancerAuthors - Yonger Chen |
| human,mouse | WB | Nat Commun Phenazine biosynthesis-like domain-containing protein (PBLD) and Cedrelone promote antiviral immune response by activating NF-ĸBAuthors - Peili Hou
|
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