相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 亚型:
IgG1, kappa
- 保存条件:
Store at 2-8°C. Stable for one year after shipment.
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
human
- 宿主:
Mouse
- 应用范围:
FC
- 靶点:
CD35
- 抗体英文名:
Anti-Human CD35 (E11)
- 抗体名:
Anti-Human CD35 (E11)
- 规格:
100ug/500ug
| 规格: | 100ug | 产品价格: | ¥990.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥2970.0 |
经过测试的应用
| Positive FC detected in | human PBMCs |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 0.2 ug per 10^6 cells in 100 μl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
65254-1-Ig targets CD35 in FC applications and shows reactivity with human samples.
| 经测试应用 | FC |
| 经测试反应性 | human |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Mouse / IgG1, kappa |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | complement component (3b/4b) receptor 1 (Knops blood group) |
| 别名 | KN, E11, CR1, Complement receptor type 1, C3BR |
| 计算分子量 | 224 kDa |
| GenBank蛋白编号 | NM_000573 |
| 基因名称 | CR1 |
| Gene ID (NCBI) | 1378 |
| ENSEMBL Gene ID | ENSG00000203710 |
| RRID | AB_3084912 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Affinity purification |
| UNIPROT ID | P17927 |
| 储存缓冲液 | PBS with 0.09% sodium azide, pH 7.3. |
| 储存条件 | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
CD35, also known as complement receptor type 1 (CR1) or C3b/C4b receptor, is a single-chain glycoprotein consisting of 30 repeating homologous protein domains known as short consensus repeats (~60 amino acids each) followed by transmembrane and cytoplasmic domains (PMID: 8765013). CD35 is variably expressed by granulocytes, monocytes, B cells, some T cells, erythrocytes, follicular dendritic cells, Langerhans cells, and glomerular podocytes (PMID: 19004497). CD35 acts as a receptor for C3b and C4b and plays important roles in the regulation of the complement cascade and clearance of immune complexes.
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验CD35 分子 CD35 常用单克隆抗体或代号: TO5,E11;(CR1) 主要表达细胞: G,M,DC,B,NKsubRBC [M] 分子质量(kDa)和结构: p250(含CCP结构域) 功 能: 结合C3b和C4b,调理吞噬,红细胞免疫粘附,调节B细胞活化 CD35 Aka CR1, C3b and C4b receptor Mediates adherence
的分子,如CD2、CD4、CD8、CD28、CD31、CD50、CD54、CD56、CD58、CD80、CD102、CD106等。 (5)有CD命名的CR有CR1(CD35)、CR2(CD21)、CR3(CD11b\CD18)、CR4(CD11c/CD18)和C5aR(CD88),其中CR3和CR4属于粘附分子中整合素超家族成员。 (6)有CD编号的CKR有CD115~CDw130;属于IGSF结构的CKR有CD115、CD
网络 二、I型补体受体(CD35) I型补体受体(CR1、C3b/C受体,又称CD35) 为单链穿膜糖蛋白,分子量160-260kDa。CRI有四种同种异型,其分子量与基因频率分别为,A:190kDa(0.83)、B:220kDa(0.16)、C:160kDa(0.01)和D:260kDa(0.002),但它们的功能相同。CR1广泛分布
技术资料暂无技术资料 索取技术资料










