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- 文献和实验
- 技术资料
- 亚型:
IgG
- 保存条件:
Store at 2-8°C. Stable for one year after shipment.
- 克隆性:
Recombinant
- 标记物:
Unconjugated
- 适应物种:
mouse
- 宿主:
Rabbit
- 应用范围:
FC (Intra)
- 靶点:
IL-12/IL-23 p40
- 抗体英文名:
Anti-Mouse IL-12/IL-23 p40 Rabbit Recombinant Antibody
- 抗体名:
Anti-Mouse IL-12/IL-23 p40 Rabbit Recombinant Antibody
- 规格:
100ug/500ug/1mg
| 规格: | 100ug | 产品价格: | ¥600.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥2200.0 |
| 规格: | 1mg | 产品价格: | ¥3000.0 |
经过测试的应用
| Positive FC (Intra) detected in | IFNγ and LPS treated RAW 264.7 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.25 ug per 10^6 cells in 100 μl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
98004-1-RR targets IL-12/IL-23 p40 in FC (Intra) applications and shows reactivity with mouse samples.
| 经测试应用 | FC (Intra) |
| 经测试反应性 | mouse |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | IL-12/IL-23 p40 |
| 别名 | Il12b, Il-12b, IL-12 p40, Il 12p40, Il 12b |
| 计算分子量 | 70 kDa |
| 基因名称 | |
| Gene ID (NCBI) | |
| RRID | AB_3672148 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P43432 |
| 储存缓冲液 | PBS with 0.09% sodium azide, pH 7.3. |
| 储存条件 | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
IL-12 and IL-23 are heterodimeric cytokines that share a common p40 subunit (PMID: 11114383). IL-12 is composed of the IL-12 p40 subunit linked to the IL-12 p35 subunit, and the heterodimer signals through the IL-12 receptor (IL-12R), which comprises the IL-12Rβ1 and IL-12Rβ2 subunits. IL-23 is composed of the IL-23 p19 subunit and the IL-12 p40 (IL-12/23p40) subunit, which signals through IL-23R and IL-12Rβ1 (PMID: 11114383; 26121196 ). IL-12/IL-23 p40 also exists as a monomer and as a homodimer which can act as a potent IL-12 antagonist (PMID: 8958912; 18783467). IL-12/IL-23 p40 is produced by antigen-presenting cells, such as dendritic cells (DCs), monocytes, macrophages, neutrophils and, to a lesser extent, B cells (PMID: 20476918).
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文献和实验ANTIBODY BINDING TO PROTEIN A AND PROTEIN G
of various immunoglobulines. Protein A is a 42 kDa polypeptide that binds the residues in the CH2 and CH3 domains of immunoglobulin heavy chains. Protein G is an approximatley 30 kDa polypeptide that binds immunoglobulins and albumin. Recombinant protein G
K300008RR-HRP ActivAbTMAnti-β-Tubulin Recombinant Antibody-HRP SIHCZ-0409 β-Tubulin 即用型免疫组化试剂 SE134 ActivAbTM Goat Anti-Rabbit IgG/HRP SE131 ActivAbTM Goat Anti-Mouse IgG/HRP PR1910 彩虹180广谱蛋白 Marker(11-180KD) PC
secondary antibody review -- data from 99 publications
Signaling 18 IgG Alexa Fluor 488 immunocytochemistry 1:2000 18 IgG Alexa Fluor 568 immunocytochemistry 1:2000 19 donkey IgG HRP western blot 1:3000 detect antibody binding in mouse epithelial cells Amersham Biosciences 19 goat
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