- ￥1130 - 3320
- Proteintech
- 65252-1-Ig
- 2025年10月09日
- FC, ELISA
- Mouse
- Human
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 亚型：
IgG1, kappa
- 保存条件：
Store at 2-8°C. Stable for one year after shipment.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human
- 宿主：
Mouse
- 应用范围：
FC, ELISA
- 靶点：
CD49b
- 抗体英文名：
Anti-Human CD49b (AK7)
- 抗体名：
Anti-Human CD49b (AK7)
- 规格：
100ug/500ug
| 规格： | 100ug | 产品价格： | ￥1130.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥3320.0 |
经过测试的应用
| Positive FC detected in | human PBMCs |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 0.2 ug per 10^6 cells in 100 μl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
65252-1-Ig targets CD49b in FC, ELISA applications and shows reactivity with Human samples.
| 经测试应用 | FC, ELISA |
| 经测试反应性 | Human |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Mouse / IgG1, kappa |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| 别名 | BR, CD49B, Collagen receptor, GPIa, Integrin alpha 2, ITGA2, VLA 2, VLA 2 subunit alpha, VLAA2 |
| 计算分子量 | 126 kDa |
| GenBank蛋白编号 | NM_002203 |
| 基因名称 | Integrin alpha 2 |
| Gene ID (NCBI) | 3673 |
| RRID | AB_3670283 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Affinity purification |
| UNIPROT ID | P17301 |
| 储存缓冲液 | PBS with 0.09% sodium azide, pH 7.3. |
| 储存条件 | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
CD49b, also known as alpha2 integrin, is a type I transmembrane glycoprotein which forms an adhesion molecule VLA-2 with beta1 integrin. CD49b is a receptor for many (extracellular) matrix and non-matrix molecules (PMID: 23847623). CD49b is expressed on numerous cell types including platelets, activated T cells, B cells, and monocytes. CD49b activation skews NK cell effector function to a phenotype that exhibits elevated IFN-γ production with a concomitant inhibition of motility and cytolytic function (PMID: 32971468, 32762681). The Anti-Human CD49b antibody, clone AK7, is derived from Human platelets.
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验免疫分子的命名根据不同的角度往往有不同的归类和命名，图3-3归纳了人白细胞分化抗原（CD）、粘附分子（AM）、免疫球蛋白超家族（IGSF）、细胞因子受体（CKR）、补体受体（CR）以及主要组织相容性复合体抗原（MHC）等免疫分子命名的相互关系。 （1）A表示CD命名范围中的粘附分子，如CD49a/CD29、CD49b/CD29、CD49c/CD29、CD49d/CD29、CD
网络 二、Ig超家族的特点 （一）Ig超家族的结构特点 Ig超家族成员均含有1～7个Ig样结构域，每个Ig样结构域约含70～110个氨基酸残基。其二级结构是两个各含3～5个反平行β折叠股所形成的β片层（anti-parallel β-pleated sheet)平面，每个反平行β折叠股由5～10个氨基酸残基组成，β
Purifying and Measuring Immunoglobulin E (IgE) and Anti-IgE
of enzyme-linked immunosorbent assays (ELISAs) and monoclonal antibody technology has proven instrumental for advancing the science of Ig biology. IgE is of interest as it is the primary Ig responsible for allergic reactions ranging from allergic rhinitis
技术资料暂无技术资料 索取技术资料
