- ￥5800
- Proteintech
- 65283-1-PBS
- 2025年10月09日
- FC (Intra)
- Mouse
- human
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- 详细信息
- 技术资料
- 亚型：
IgG1
- 保存条件：
Store at -80°C.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
human
- 宿主：
Mouse
- 应用范围：
FC (Intra)
- 靶点：
M-CSF
- 抗体英文名：
Anti-Human M-CSF (3G12E6), PBS Only
- 抗体名：
Anti-Human M-CSF (3G12E6), PBS Only
- 规格：
100ug
65283-1-Ig
产品信息
65283-1-PBS targets M-CSF in FC (Intra) applications and shows reactivity with human samples.
| 经测试应用 | FC (Intra) |
| 经测试反应性 | human |
| 免疫原 | fusion protein |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | colony stimulating factor 1 (macrophage) |
| 别名 | 3G12E6, CSF 1, CSF1, CSF-1, Lanimostim |
| 计算分子量 | 60 kDa |
| GenBank蛋白编号 | BC021117 |
| 基因名称 | M-CSF |
| Gene ID (NCBI) | 1435 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | P09603 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
M-CSF plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes. M-CSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. On the cellular level, M-CSF promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration and plays a role in lipoprotein clearance (PMID: 29734839; 29679908; 28202039)
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