- ￥740 - 2230
- Proteintech
- 65217-1-Ig
- 2025年10月09日
- FC
- Mouse
- rat
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- 详细信息
- 技术资料
- 亚型：
IgG1, kappa
- 保存条件：
Store at 2-8°C. Stable for one year after shipment.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
rat
- 宿主：
Mouse
- 应用范围：
FC
- 靶点：
CD80
- 抗体英文名：
Anti-Rat CD80 (3H5)
- 抗体名：
Anti-Rat CD80 (3H5)
- 规格：
100ug/500ug
| 规格： | 100ug | 产品价格： | ￥740.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥2230.0 |
经过测试的应用
| Positive FC detected in | LPS-stimulated Wistar rat splenocytes |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 1 ug per 10^6 cells in 100 μl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
65217-1-Ig targets CD80 in FC applications and shows reactivity with rat samples.
| 经测试应用 | FC |
| 经测试反应性 | rat |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Mouse / IgG1, kappa |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | Cd80 molecule |
| 别名 | Cd80 molecule, B7-1, B7.1, B7 1, 3H5 |
| 计算分子量 | 36 kDa |
| GenBank蛋白编号 | XM_017597885 |
| 基因名称 | CD80 |
| Gene ID (NCBI) | 25408 |
| RRID | AB_2935142 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | G3V671 |
| 储存缓冲液 | PBS with 0.09% sodium azide, pH 7.3. |
| 储存条件 | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
CD80 (also known as B7-1) is a type I membrane protein that is a member of the immunoglobulin superfamily, with an extracellular immunoglobulin constant-like domain and a variable-like domain required for receptor binding. It is expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, monocytes, and macrophages. CD80 is the receptor for the proteins CD28 and CTLA-4 found on the surface of T-cells. It is involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. CD80 also acts as a cellular attachment receptor for adenovirus subgroup B. (PMID: 7545666; 12015893; 16920215)
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