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- 详细信息
- 文献和实验
- 技术资料
- 亚型:
IgG1, kappa
- 保存条件:
Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性:
Monoclonal
- 标记物:
CoraLite® Plus 750 Fluorescent Dye
- 适应物种:
Human
- 宿主:
Mouse
- 应用范围:
FC
- 靶点:
CD18
- 抗体英文名:
CoraLite® Plus 750 Anti-Human CD18 (TS1/18)
- 抗体名:
CoraLite® Plus 750 Anti-Human CD18 (TS1/18)
- 规格:
25tests/100tests
| 规格: | 25tests | 产品价格: | ¥1210.0 |
|---|---|---|---|
| 规格: | 100tests | 产品价格: | ¥3020.0 |
经过测试的应用
| Positive FC detected in | human PBMCs |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 5 ul per 10^6 cells in 100 μl suspension |
| This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 μl per 10^6 cells in a 100 µl suspension or 5 μl per 100 µl of whole blood. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL750-65190 targets CD18 in FC applications and shows reactivity with Human samples.
| 经测试应用 | FC |
| 经测试反应性 | Human |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Mouse / IgG1, kappa |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| 别名 | CD18, Integrin beta 2, ITGB2, LAD, LCAMB, LFA 1, MAC 1, MF17, MFI7 |
| 计算分子量 | 85 kDa |
| GenBank蛋白编号 | BC005861 |
| 基因名称 | CD18 |
| Gene ID (NCBI) | 3689 |
| ENSEMBL Gene ID | ENSG00000160255 |
| RRID | AB_2924098 |
| 偶联类型 | CoraLite® Plus 750 Fluorescent Dye |
| 最大激发/发射波长 | 755 nm / 780 nm |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | P05107 |
| 储存缓冲液 | PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. |
| 储存条件 | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
CD18, also known as integrin beta-2, is a transmembrane protein that forms heterodimers with CD11a, CD11b, CD11c, CD11d (PMID: 1968349). CD11a/CD18 (LFA-1) is expressed by all leukocytes, while CD11b/CD18 (Mac-1) and CD11c/CD18 (p150,95) are normally restricted to expression on monocytes, macrophages, polymorphonuclear lymphocytes (PMNs), and natural killer cells (PMID: 1968349; 3109455; 10946284). CD18 plays an important role in mediating cell adhesion during immune response and defects of CD18 cause leukocyte adhesion deficiency (PMID: 3594570).
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文献和实验3,717 −1.87** 10,223 3,700 −1.76*** 10,686 3,477 −2.07*** 10,466 4,538 −1.31*** HS_98 3,274 1,065 −2.08** 3,225 859 −2.76*** 3,445 965 −2.57*** 2,850 750 −2.80*** hsa-miR-340 4,583 1,443 −2.18
Endothelial Cell Systems - Instructions For Use
Extract (BBE) supplement. EGM® is a modified MCDB 131 formulation and is supplied fully supplemented with the following: (amounts indicate final concentration, except BBE) 10 ng/ml hEGF (human recombinant Epidermal Growth Factor) 1.0 µg/ml
低, 通常1 cm 2 只有400 个探针。 另外还有一种三维芯片[ 18, 19 ] , 是由美国的Packard 公司、Motorola 公司、Argonne 国家实验室与俄罗斯Engelhardt 分子生物学研究所合作开发的一种芯片技术, 也可以认为是合成后交联技术的一种。 这种三维芯片主要是利用官能团化的聚丙烯酰胺凝胶块作为基质来固定寡核苷酸。 这种三维芯片具有明显的优点: 固定的寡核苷酸量比较大, 每一种探针为3- 300 fmol, 是二维芯片样品量的100 倍, 被检测样品DNA 分子
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