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- 详细信息
- 技术资料
- 亚型:
IgG
- 保存条件:
Store at -80°C.
- 克隆性:
Recombinant
- 标记物:
Unconjugated
- 适应物种:
human
- 宿主:
Rabbit
- 应用范围:
FC
- 靶点:
B7-H3/CD276
- 抗体英文名:
Anti-Human B7-H3/CD276 Rabbit Recombinant Antibody, PBS Only
- 抗体名:
Anti-Human B7-H3/CD276 Rabbit Recombinant Antibody, PBS Only
- 规格:
500ug/1mg
| 规格: | 500ug | 产品价格: | ¥3600.0 |
|---|---|---|---|
| 规格: | 1mg | 产品价格: | ¥5000.0 |
产品信息
98017-1-PBS targets B7-H3/CD276 in FC applications and shows reactivity with human samples.
| 经测试应用 | FC |
| 经测试反应性 | human |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | CD276 molecule |
| 别名 | CD276, B7-H3, B7H3, B7 homolog 3, B7 H3 |
| 计算分子量 | 57 kDa |
| GenBank蛋白编号 | NM_001024736 |
| 基因名称 | CD276 |
| Gene ID (NCBI) | 80381 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purfication |
| UNIPROT ID | Q5ZPR3 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
B7-H3 (CD276) is a type I transmembrane protein expressed on many tissues and cell types. B7-H3 is a 100-kDa glycoprotein that belongs to the B7 immunoregulatory family and participates in the regulation of T-cell-mediated immune response probably by functioning as both a T cell costimulator and coinhibitor (PMID: 25567370; 20696859). Overexpressed on a wide range of human solid cancers, B7-H3 has been implicated in cancer progression and metastasis and becomes an attractive target for cancer immunotherapy (PMID: 27208063).
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