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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant Mouse IFN-alpha 2/IFNA2 protein (rFc Tag) (HPLC verified)
- 亚型:
IgG
- 保存条件:
Store at -20°C. Stable for one year after shipment.
- 克隆性:
Polyclonal
- 标记物:
Unconjugated
- 适应物种:
mouse
- 宿主:
Rabbit
- 应用范围:
WB, ELISA
- 靶点:
IFN alpha2
- 抗体英文名:
IFN alpha2 Polyclonal antibody
- 抗体名:
IFN alpha2 Polyclonal antibody
- 规格:
50ul/100ul/150ul
| 规格: | 50ul | 产品价格: | ¥1350.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥2200.0 |
| 规格: | 150ul | 产品价格: | ¥3000.0 |
经过测试的应用
| Positive WB detected in | Recombinant protein |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:4000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
32673-1-AP targets IFN alpha2 in WB, ELISA applications and shows reactivity with mouse samples.
| 经测试应用 | WB, ELISA |
| 经测试反应性 | mouse |
| 免疫原 |
CatNo: Eg3079 Product name: Recombinant Mouse IFN-alpha 2/IFNA2 protein (rFc Tag) (HPLC verified) Source: mammalian cells-derived, V37 Tag: C-rFc Domain: 24-190 aa of Sequence: CDLPHTYNLRNKRALKVLAQMRRLPFLSCLKDRQDFGFPLEKVDNQQIQKAQAIPVLRDLTQQTLNLFTSKASSAAWNATLLDSFCNDLHQQLNDLQTCLMQQVGVQEPPLTQEDALLAVRKYFHRITVYLREKKHSPCAWEVVRAEVWRALSSSVNLLPRLSEEKE |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | interferon alpha 2 |
| 别名 | Ifna2, IFN-alpha 2, IFN-alpha-2, Interferon alpha 2, Interferon alpha-2 |
| 计算分子量 | 22 kDa |
| 基因名称 | Ifna2 |
| Gene ID (NCBI) | 15965 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | P01573 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
IFN-alpha2 (Interferon-alpha 2) is a subtype of the Type I interferon family, which plays a critical role in the immune response to viral infections and certain cancers. It is a cytokine that signals through the IFNAR receptor complex (IFNAR1 and IFNAR2) to activate the JAK-STAT signaling pathway, leading to the expression of interferon-stimulated genes (ISGs). These genes have antiviral, antiproliferative, and immunomodulatory effects.
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文献和实验Measuring Interferon Alpha and Other Cytokines in SLE
The progression of disease in patients with systemic lupus erythematosus (SLE) is affected by production, accumulation, and actions of cytokines. Type I interferon (IFN), specifically IFN-α, is recognized as a central mediator of disease
motifs located prevalently in the 3′ untranslated regions of target messenger RNAs (mRNA). Interferon-alpha-2a (IFNα) induces a large set of protein coding genes mediating antiproliferative and antiviral responses. Here we use a global microarray-based
tumor necrosis factor–{alpha} (TNF-{alpha}), interferon-beta (IFN-beta), and IFN-{gamma} (1). The authors observed that of ~200 miRNAs examined, only miR-155 increased in amount in response to both TLR ligands and IFN-beta. miR-155 accumulated
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