- ￥1000 - 2490
- Proteintech
- CR-65254
- 2025年10月09日
- FC
- Mouse
- human
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
IgG1, kappa
- 保存条件：
Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性：
Monoclonal
- 标记物：
Cardinal Red™ Fluorescent Dye
- 适应物种：
human
- 宿主：
Mouse
- 应用范围：
FC
- 靶点：
CD35
- 抗体英文名：
Cardinal Red™ Anti-Human CD35 (E11)
- 抗体名：
Cardinal Red™ Anti-Human CD35 (E11)
- 规格：
25tests/100tests
| 规格： | 25tests | 产品价格： | ￥1000.0 |
|---|---|---|---|
| 规格： | 100tests | 产品价格： | ￥2490.0 |
经过测试的应用
| Positive FC detected in | human PBMCs |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 5 ul per 10^6 cells in 100 μl suspension |
| This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 µl per 10^6 cells in a 100 µl suspension or 5 µl per 100 µl of whole blood. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CR-65254 targets CD35 in FC applications and shows reactivity with human samples.
| 经测试应用 | FC |
| 经测试反应性 | human |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Mouse / IgG1, kappa |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | complement component (3b/4b) receptor 1 (Knops blood group) |
| 别名 | KN, E11, CR1, Complement receptor type 1, C3BR |
| 计算分子量 | 224 kDa |
| GenBank蛋白编号 | NM_000573 |
| 基因名称 | CR1 |
| Gene ID (NCBI) | 1378 |
| ENSEMBL Gene ID | ENSG00000203710 |
| RRID | AB_3084987 |
| 偶联类型 | Cardinal Red™ Fluorescent Dye |
| 最大激发/发射波长 | 592 nm / 611 nm |
| 形式 | Liquid |
| 纯化方式 | N/A |
| UNIPROT ID | P17927 |
| 储存缓冲液 | PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. |
| 储存条件 | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
CD35, also known as complement receptor type 1 (CR1) or C3b/C4b receptor, is a single-chain glycoprotein consisting of 30 repeating homologous protein domains known as short consensus repeats (~60 amino acids each) followed by transmembrane and cytoplasmic domains (PMID: 8765013). CD35 is variably expressed by granulocytes, monocytes, B cells, some T cells, erythrocytes, follicular dendritic cells, Langerhans cells, and glomerular podocytes (PMID: 19004497). CD35 acts as a receptor for C3b and C4b and plays important roles in the regulation of the complement cascade and clearance of immune complexes.
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文献和实验CD35 分子 CD35 常用单克隆抗体或代号： TO5,E11;(CR1) 主要表达细胞： G,M,DC,B,NKsubRBC [M] 分子质量(kDa)和结构： p250(含CCP结构域) 功 能： 结合C3b和C4b,调理吞噬,红细胞免疫粘附,调节B细胞活化 CD35 Aka CR1, C3b and C4b receptor Mediates adherence
.1993;151(1):377-388. 4.F.S.罗森等编著，朱立平等编译《现代免疫学词典》，科学出版社，北京，1993年4月第1版. 5.Roitt I.M.Eucyclopedia of Immunology,Academic press.London.1992;63-66;371-391. 6.Fallman M,et al.Signaling properties of CR3(CD11b/CD18)and CR1(CD35)in relation
.67144-12.7394-17.1Human1724.1846.7-4.183.785.1633.5-7.5168-2.2Human229.8-2.6829.8-2.7625.1-5.08151-11.7287-9.1Bio-Red1630391.287.1024-14.62522Bio-Red2421.7927018.0-4.44201-14.32980.84* 从总蛋白结果来看RANBOX与Bio-Red 相差为6.45%，而宝灵曼与Bio-Red 较为接近；* 从白蛋白结果分析，宝灵曼与Bio
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