CoraLite® Plus 750 Anti-Human CD42b (AK2)  CL750-65163

CoraLite® Plus 750 Anti-Human

CD42b (AK2) CL750-65163
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  • ¥1240 - 3100
  • Proteintech已认证
  • CL750-65163
  • 2025年10月09日
  • FC
  • Mouse
  • human
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    • 详细信息
    • 技术资料
    • 亚型

      IgG1

    • 保存条件

      Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

    • 克隆性

      Monoclonal

    • 标记物

      CoraLite® Plus 750 Fluorescent Dye

    • 适应物种

      human

    • 宿主

      Mouse

    • 应用范围

      FC

    • 靶点

      CD42b

    • 抗体英文名

      CoraLite® Plus 750 Anti-Human CD42b (AK2)

    • 抗体名

      CoraLite® Plus 750 Anti-Human CD42b (AK2)

    • 规格

      25tests/100tests

    规格:25tests产品价格:¥1240.0
    规格:100tests产品价格:¥3100.0

    经过测试的应用

    Positive FC detected inhuman peripheral blood platelets
    For other applications, we recommend the unconjugated version of this antibody, 65163-1-Ig

    推荐稀释比

    应用推荐稀释比
    Flow Cytometry (FC)FC : 5 ul per 10^6 cells in 100 μl suspension
    This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
    Sample-dependent, Check data in validation data gallery.

    产品信息

    CL750-65163 targets CD42b in FC applications and shows reactivity with human samples.

    经测试应用 FC
    经测试反应性 human
    免疫原

    fusion protein

    宿主/亚型 Mouse / IgG1
    抗体类别 Monoclonal
    产品类型 Antibody
    全称 glycoprotein Ib (platelet), alpha polypeptide
    别名 GP1BA, GP1B, CD42b alpha, BSS, Antigen CD42b-alpha
    计算分子量 626 aa, 69 kDa
    GenBank蛋白编号BC027955
    基因名称 CD42b
    Gene ID (NCBI) 2811
    ENSEMBL Gene IDENSG00000185245
    RRIDAB_2935108
    偶联类型 CoraLite® Plus 750 Fluorescent Dye
    最大激发/发射波长755 nm / 780 nm
    形式Liquid
    纯化方式Purified by protein-A affinity chromatography
    UNIPROT IDP07359
    储存缓冲液 PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3.
    储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

    背景介绍

    CD42b, also known as platelet glycoprotein Ib alpha chain (GPIb alpha), is a type I transmembrane glycoprotein of 135-145 kDa (PMID: 2656709). It is expressed on platelets and megakaryocytes. CD42b and CD42c (GPIb beta) are linked by a disulphide bond to form GPIb (PMID: 7660135). GPIb forms a noncovalent complex with CD42a (GPIX) and CD42d (GPV) and acts as a receptor for von Willebrand factor (vWF) and thrombin (PMID: 7660135; 3759960). The GPIb-V-IX complex mediates vWF-dependent platelet adhesion to blood vessels. Defects in the expression of CD42b result in Bernard-Soulier syndromes and platelet-type von Willebrand disease (PMID: 9371310).

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