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CoraLite® Plus 750 Anti-Mouse

MHC Class II (I-A/I-E) (M5/114.15.2) CL750-65122
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  • ¥800 - 1990
  • Proteintech已认证
  • CL750-65122
  • 2025年10月09日
  • FC
  • Rat
  • mouse
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 亚型

      IgG2b, kappa

    • 保存条件

      Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

    • 克隆性

      Monoclonal

    • 标记物

      CoraLite® Plus 750 Fluorescent Dye

    • 适应物种

      mouse

    • 宿主

      Rat

    • 应用范围

      FC

    • 靶点

      MHC Class II (I-A/I-E)

    • 抗体英文名

      CoraLite® Plus 750 Anti-Mouse MHC Class II (I-A/I-E) (M5/114.15.2)

    • 抗体名

      CoraLite® Plus 750 Anti-Mouse MHC Class II (I-A/I-E) (M5/114.15.2)

    • 规格

      25ug/100ug

    规格:25ug产品价格:¥800.0
    规格:100ug产品价格:¥1990.0

    经过测试的应用

    Positive FC detected inmouse splenocytes
    For other applications, we recommend the unconjugated version of this antibody, 65122-1-Ig

    推荐稀释比

    应用推荐稀释比
    Flow Cytometry (FC)FC : 0.25 ug per 10^6 cells in a 100 µl suspension
    This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
    Sample-dependent, Check data in validation data gallery.

    产品信息

    CL750-65122 targets MHC Class II (I-A/I-E) in FC applications and shows reactivity with mouse samples.

    经测试应用 FC
    经测试反应性 mouse
    免疫原

    fusion protein

    宿主/亚型 Rat / IgG2b, kappa
    抗体类别 Monoclonal
    产品类型 Antibody
    全称 histocompatibility 2, class II antigen A, alpha
    别名 H2Aa, Aalpha, H 2Aa, H2-Aa, Ia 1
    GenBank蛋白编号BC031711
    基因名称 MHC Class II
    Gene ID (NCBI) 14960
    RRIDAB_2935099
    偶联类型 CoraLite® Plus 750 Fluorescent Dye
    最大激发/发射波长755 nm / 780 nm
    形式Liquid
    纯化方式Affinity purification
    UNIPROT IDP14434
    储存缓冲液 PBS with 0.09% sodium azide, pH 7.3.
    储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

    背景介绍

    Major histocompatibility complex (MHC) class II molecules are heterodimeric transmembrane glycoproteins that are expressed on the surface of antigen-presenting cells such as dendritic cells, macrophages, and B cells. The M5/114.15.2 antibody detects polymorphic determinants present on B cells, monocytes, macrophages, dendritic cells, and activated T lymphocytes from mice carrying the H-2b, H-2d, H-2q, H-2p, H-2r and H-2u haplotypes but not from mice carrying the H-2s or H-2f haplotypes (PMID: 6170707). This antibody recognizes both I-A and I-E subregion-encoded Ia glycoproteins (I-Ab, I-Ad, I-Aq, I-Ed, I-Ek, not I-Af, I-Ak, or I-As). M5/114 mAb is reported to inhibit I-A subregion-restricted T cell responses of the H-2b, H-2d, H-2q, H-2u but not the H-2f, H-2k, H-2s haplotypes (PMID: 6173436).

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    图标文献和实验
    相关实验
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    • BIO-RAD(伯乐)电泳仪、电泳槽

      使用者最大凝胶尺寸(W x L) 24 x 16 cm缓冲液要求200 ml凝胶容量≤3 块PROTEAN® II 凝胶三明治*3 块Criterion™ 凝胶4 块Mini-PROTEAN® 3 凝胶4 块Ready Gel® 预制胶 电源PowerPac™ HC 电源简介: 体积(W x L x H) 37 x 24 x 11 cm Sequi-Gen GT 测序电泳槽简介: 拥有专利* Sequi-Gen GT 测序电泳槽使测序胶的铺制和电泳变得更简单。系统设计避免

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    CoraLite® Plus 750 Anti-Mouse MHC Class II (I-A/I-E) (M5/114.15.2) CL750-65122
    ¥800 - 1990