- ￥2800
- Proteintech
- CL488-68618
- 2025年10月09日
- IF/ICC
- Mouse
- human, mouse
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- 详细信息
- 技术资料
- 免疫原：
Recombinant human ANGPT1 protein
- 亚型：
IgG1
- 保存条件：
Store at -20°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性：
Monoclonal
- 标记物：
CoraLite® Plus 488 Fluorescent Dye
- 适应物种：
human, mouse
- 宿主：
Mouse
- 应用范围：
IF/ICC
- 靶点：
Angiopoietin 1
- 抗体英文名：
CoraLite® Plus 488-conjugated Angiopoietin 1 Monoclonal antibody
- 抗体名：
CoraLite® Plus 488-conjugated Angiopoietin 1 Monoclonal antibody
- 规格：
100ul
经过测试的应用
| Positive IF/ICC detected in | HeLa cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL488-68618 targets Angiopoietin 1 in IF/ICC applications and shows reactivity with human, mouse samples.
| 经测试应用 | IF/ICC |
| 经测试反应性 | human, mouse |
| 免疫原 |
CatNo: Ag18829 Product name: Recombinant human ANGPT1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 161-293 aa of BC152411 Sequence: IQLLENSLSTYKLEKQLLQQTNEILKIHEKNSLLEHKILEMEGKHKEELDTLKEEKENLQGLVTRQTYIIQELEKQLNRATTNNSVLQKQQLELMDTVHNLVNLCTKEGVLLKGGKREEEKPFRDCADVYQAG |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | angiopoietin 1 |
| 别名 | ANGPT1, 3C4A3, AGP1, AGPT, ANG 1 |
| 计算分子量 | 498 aa, 58 kDa |
| 观测分子量 | 70 kDa, 55 kDa |
| GenBank蛋白编号 | BC152411 |
| 基因名称 | Angiopoietin 1 |
| Gene ID (NCBI) | 284 |
| RRID | AB_3673026 |
| 偶联类型 | CoraLite® Plus 488 Fluorescent Dye |
| 最大激发/发射波长 | 493 nm / 522 nm |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | Q15389 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Angiopoietin 1 is a 70-kDa secreted glycoprotein generated from vascular mural cells, pericytes, and certain other cells. Angiopoietin 1 participates in vascular differentiation through angiogenesis, which is the process of the growth and remodelling of existing vessels. Angiopoietin 1 is also involved in the maintenance and turnover of blood vessels in mature animals. Angiopoietin 1 binds to and activates the TEK/TIE2 receptor by inducing its dimerization and tyrosine phosphorylation, playing an important role in the regulation of angiogenesis. Overexpression of Angiopoietin 1 has been proven to occur in malignant glioblastoma, neuroblastoma, non-small cell lung cancer, and other tumors.
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