- ￥2800
- Proteintech
- CL488-80165
- 2025年10月09日
- IF-P
- Rabbit
- Human, Mouse, Rat
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- 详细信息
- 技术资料
- 免疫原：
Recombinant human TMEM173 protein
- 亚型：
IgG
- 保存条件：
Store at -20°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性：
Recombinant
- 标记物：
CoraLite® Plus 488 Fluorescent Dye
- 适应物种：
Human, Mouse, Rat
- 宿主：
Rabbit
- 应用范围：
IF-P
- 靶点：
TMEM173/STING
- 抗体英文名：
CoraLite® Plus 488-conjugated TMEM173/STING Recombinant monoclonal antibody
- 抗体名：
CoraLite® Plus 488-conjugated TMEM173/STING Recombinant monoclonal antibody
- 规格：
100ul
经过测试的应用
| Positive IF-P detected in | human tonsillitis tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL488-80165 targets TMEM173/STING in IF-P applications and shows reactivity with Human, Mouse, Rat samples.
| 经测试应用 | IF-P |
| 经测试反应性 | Human, Mouse, Rat |
| 免疫原 |
CatNo: Ag13921 Product name: Recombinant human TMEM173 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 174-379 aa of BC047779 Sequence: ELQARIRTYNQHYNNLLRGAVSQRLYILLPLDCGVPDNLSMADPNIRFLDKLPQQTGDHAGIKDRVYSNSIYELLENGQRAGTCVLEYATPLQTLFAMSQYSQAGFSREDRLEQAKLFCRTLEDILADAPESQNNCRLIAYQEPADDSSFSLSQEVLRHLRQEEKEEVTVGSLKTSAVPSTSTMSQEPELLISGMEKPLPLRTDFS |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | transmembrane protein 173 |
| 别名 | FLJ38577, hMITA, hSTING, Mediator of IRF3 activation, MITA, MPYS, STING, TMEM173, transmembrane protein 173 |
| 计算分子量 | 379 aa, 42 kDa |
| 观测分子量 | 37 kDa |
| GenBank蛋白编号 | BC047779 |
| 基因名称 | STING |
| Gene ID (NCBI) | 340061 |
| RRID | AB_2919576 |
| 偶联类型 | CoraLite® Plus 488 Fluorescent Dye |
| 最大激发/发射波长 | 493 nm / 522 nm |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q86WV6 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Stimulator of interferon genes (STING, also known as ERIS, MITA and MPYS, and encoded by TMEM173) is a transmembrane adaptor protein that facilitates innate immune signaling (PMID: 18724357). STING is widely expressed in various cell types such as endothelial cells, epithelial cells, T cells, macrophages, and dendritic cells (PMID: 26603901). It is predominantly located in the endoplasmic reticulum (ER). STING functions as a sensor of cytosolic DNA and promotes the production of type I interferons and pro-inflammatory cytokines.
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