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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
Amyloid Precursor Protein Rabbit mAb
- 抗体英文名:
Amyloid Precursor Protein Rabbit mAb
- 应用范围:
WB IHC ICC/IF
- 宿主:
Recombinant Rabbit
- 适应物种:
Human;Mouse;Rat
- 抗原来源:
Recombinant Rabbit
- 供应商:
南京赛戈巍生物科技有限公司
- 保存条件:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- 亚型:
Rabbit IgG
- 免疫原:
A synthetic peptide of human Amyloid Precursor Protein
purification
Affinity Purified
applications
WB IHC ICC/IF
appl_detail
WB: 1/1000;
other_names
ABPP;APPI;Alzheimer disease amyloid protein;Amyloid precursor protein
calculated_mw
87 kDa
sdspage_mw
105 kDa
formulation
50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
uniprot
P05067
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文献和实验Interaction of the Presenilins with the Amyloid Precursor Protein (APP)
the deposition of amyloid Aβ peptide. The latter is released from its cognate amyloid precursor protein (APP) by a two-step proteolytic conversion: first, proteolysis of APP by β-secretase, which releases the N-terminus of Aβ, and second, conversion
Posttranslational Modifications of the Amyloid Precursor Protein: Glycosylation
Many studies have demonstrated the importance of amyloid precurser protein (APP) in the pathogenesis of Alzheimer’s disease. Nonetheless, the exact mechanism by which APP contributes to the pathogenesis of Alzheimer’s disease is still not clear
Phosphorylation of Amyloid Precursor Protein (APP) Family Proteins
It has been well established that β-amyloid peptide is the principal protein component of extracellular cerebral amyloid deposits in patients with Alzheimer’s disease (1 ,2 ). β-Amyloid is derived from a large precursor protein, amyloid
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