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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Fusion protein corresponding to a region derived from internal residues of human thyroid stimulating hormone receptor
- 形态:
liquid
- 保存条件:
Store at -20˚C
- 克隆性:
Polyclonal
- 适应物种:
Human
- 保质期:
12 months
- 抗原来源:
Rabbit
- 供应商:
南京赛戈巍生物科技有限公司
- 宿主:
Rabbit
- 应用范围:
IHC
- 靶点:
Uniprot:P16473
- 抗体英文名:
TSHR Antibody
- 规格:
50ul/100ul
配方:Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
应用详情:Immunohistochemistry: 1:25-1:100
图片:

Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #35980 at dilution 1/50.
,

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using #35980 at dilution 1/50.
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文献和实验甲状腺功能亢进症(简称甲亢)是内分泌领域最常见的疾病之一,核心特征是血液循环中甲状腺激素过量,引发全身代谢亢进与交感神经兴奋,临床常表现为心悸、手抖、多汗、消瘦、易怒等一系列症状。甲亢并非单一病因导致的疾病,而是一组临床综合征。 格雷夫斯病(Graves病)是甲亢最常见病因,约占80%的病例。Graves病是一种自身免疫性疾病,患者产生针对促甲状腺激素受体(TSHR)的自身抗体(TRAb),其中刺激性抗体(TSAb)可模拟促甲状腺激素作用,与TSHR结合持续激活甲状腺细胞,导致T3/T
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
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