- 询价
- abinScience
- France
- CV029014
- 2026年03月03日
- ELISA, IHC, WB
- Rabbit
- Dog
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- 文献和实验
- 技术资料
- 免疫原：
Rabbit
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
0.01M PBS pH 7.4
- 克隆性：
Polyclonal
- 标记物：
Unconjugated
- 适应物种：
Dog
- 保质期：
1 year
- 抗原来源：
Rabbit
- 目录编号：
CV029014
- 级别：
科研级别
- 库存：
999
- 供应商：
abinScience
- 宿主：
Rabbit
- 应用范围：
ELISA, IHC, WB
- 浓度：
1mg/mL
- 靶点：
hepatitis A virus cellular receptor 2 precursor; HAVCR2
- 抗体英文名：
Anti-Dog CD366/HAVCR2/TIM-3 Polyclonal Antibody
- 抗体名：
Anti-Dog CD366/HAVCR2/TIM-3 Polyclonal Antibody
- 规格：
50ug/100ug
| Product name | Anti-Dog CD366/HAVCR2/TIM-3 Polyclonal Antibody |
|---|---|
| Catalog No. | CV029014 |
| Host species | Rabbit |
| Species reactivity | Dog |
| Immunogen | E. coli - derived recombinant dog CD366/HAVCR2/TIM-3 (Ser21-Arg189). |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Purity | \ |
| Clonality | Polyclonal |
| Isotype | IgG |
| Applications | ELISA, IHC, WB |
| Target | hepatitis A virus cellular receptor 2 precursor; HAVCR2 |
| Purification | Purified by antigen affinity column. |
| Endotoxin level | Please contact with the lab for this information. |
| Expression system | \ |
| Accession | \ |
| Protein length | \ |
| Nature | \ |
| Observed Molecular Weight | \ |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternative Names | \ |
| Clone ID | \ |
| Species | \ |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Note | For research use only |
abinScience, founded in 2023 in Strasbourg, France, is committed to developing and producing high-quality life science reagents. Rooted in one of Europe’s leading hubs for scientific innovation, abinScience empowers global research through reliable, efficient experimental solutions. Guided by the vision of “Empowering Bioscience Discovery,” we support scientists worldwide in advancing the frontiers of bioscience.
Technology and Innovation
Relying on the global leading position in antibody and protein research and more than 20 years of industry experience of its parent company ProteoGenix since 2003, abinScience has inherited advanced technologies and high-quality standards. In particular, the XtenCHO™ system developed by ProteoGenix, which has two modes of transient expression and stable expression, has been widely recognized as a core technology to improve the efficiency of protein production, providing a solid foundation for ab...
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10000+ high-activity proteins.
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DNA/RNA antibodies and PEG antibodies.
1000+ reagent kit series products.
Large-scale packaging customization services: We offer personalized antibody design, protein production, molecular optimization, and experimental development services.
Application field
Infectious disease research: including viruses, superbugs, parasites, etc.
Neuroscience research: Supporting research on neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.
Immunology research: Covers the research needs of immune activation, inhibition, and allergies and abnormal reactions.
Oncology research: Supporting the development of tumor biology and anti-tumor drugs.
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文献和实验• Spatial and multiomics analysis of human and mouse lung adenocarcinoma precursors reveals TIM-3 as a putative target for precancer interception., PMID:40345189
• Single-cell RNA-seq reveals developmental plasticity with coexisting oncogenic states and immune evasion programs in ETP-ALL., PMID:33227818
• Single-cell transcriptomic analysis of the immune microenvironment in pediatric acute leukemia., PMID:38844062
• TOX2 nuclear-cytosol translocation is linked to leukemogenesis of acute T-cell leukemia by repressing TIM3 transcription., PMID:39080376
• A TIM-3-Fc decoy secreted by engineered T cells improves CD19 CAR T-cell therapy in B-cell acute lymphoblastic leukemia., PMID:40090006
• Immune evolution in pre-invasive lung adenocarcinoma., PMID:40345186
• The role of ICOS and other costimulatory molecules in allergy and asthma., PMID:14999428
• Integrative multi-omics reveals a regulatory and exhausted T-cell landscape in CLL and identifies galectin-9 as an immunotherapy target., PMID:40775219
• The role of CD101 and Tim3 in the immune microenvironment of gastric cancer and their potential as prognostic biomarkers., PMID:39700955
-bin/carddisp.pl?gene=HAVCR2&keywords=CD366 TIM3作为重要的细胞免疫负调控因子，高表达于辅助型T细胞（Thl细胞）和细胞毒性T细胞中（Tcl细胞），并产生抑制信号从而导致Thl细胞和Tcl细胞的凋亡。其配体为半乳凝素9(Gal-9)，这是一种被广泛表达的可溶性分子[7]，与TIM3分子的免疫球蛋白可变区上的寡聚糖结合，从而对Thl驱动的免疫反应产生负调控作用。当TIM3与其配体半乳凝素9(Gal-9)结合后，促进Thl细胞凋亡[8] 。也就是说
. A rabbit polyclonal antisera is also available (101c500; BAbCO) but in our hands this was less reactive. The antibody cleanup protocol is now a seperate document Protocol Cells are grown in 5 mls of YPAD to an O.D. 600 of 0.75 to 1.
suspended in PBS. A rabbit polyclonal antisera is also available (101c500; BAbCO) but in our hands this was less reactive. The antibody cleanup protocol is now a seperate document Protocol Cells are grown in 5 mls of YPAD to an O.D. 600
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