- ￥3538
- BD
- 美国
- 571155
- 2026年10月23日
- Flow Cytometry (FCM)
- Mouse
- Human
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- 文献和实验
- 技术资料
- 供应商：
BD Pharmingen
- 级别：
RUO
- 克隆性：
单克隆
- 抗原来源：
Human
- 标记物：
RY610
- 宿主：
Mouse
- 适应物种：
Human
- 免疫原：
Human IL-3Ra-transfected cells
- 亚型：
Mouse IgG2a, κ
- 形态：
液体
- 应用范围：
Flow Cytometry (FCM)
- 保存条件：
2-8℃避光保存
- 规格：
100 Tests
产品概述
Hu CD123 (IL3RA) RY610 7G3 100Tst 为 BD Pharmingen 品牌流式抗体，货号 571155，荧光标记 RY610，克隆 7G3 (RUO)，规格 100 Tests。适用于 Flow cytometry (Routinely Tested) 检测，仅供科研使用（RUO）。
靶点与抗体说明
The 7G3 monoclonal antibody specifically recognizes human CD123, the 70 kDa IL-3 Receptor α (IL-3Rα) chain. CD123 associates with CD131, the 120-140 kDa Common β chain to form the IL-3 Receptor Complex. CD131 is shared with the receptors for interleukins IL-5 and GM-CSF. IL-3Rα is expressed on hematopoietic progenitors and plays an important role in hematopoietic progenitor cell growth and differentiation. It is also expressed by mast cells, macrophages and a CD5+ B cell subset. This antibody has been reported to block the binding of 125I-IL-3 to high and low affinity IL-3 receptors. In functional experiments, this antibody was found to inhibit acute myeloid leukemia cell proliferation, basophil histamine release, endothelial cell-mediated IL-8 secretion, and neutrophil transmigration. This antibody has been reported to be useful for immunoprecipitation, Western blot and immunofluorescent staining for flow cytometry. At the Fifth HLDA Workshop, the human IL-3 receptor was designated CD123.
核心参数
| 货号 | 571155 |
| 品牌 | BD Pharmingen |
| 克隆号 | 克隆 7G3 (RUO) |
| 宿主 | Mouse |
| 同种型 | Mouse IgG2a, κ |
| 荧光标记 | RY610 |
| 反应种属 | Human |
| 验证应用 | Flow cytometry (Routinely Tested) |
| 推荐用量 | 5 µl/test |
| 免疫原 | Human IL-3Ra-transfected cells |
| 规格 | 100 Tests |
| 存储缓冲液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
荧光染料信息
RY610 The BD Horizon RealYellow™ 610 (RY610) Dye is part of the BD® family of yellow-green dyes. It is a tandem fluorochrome with an excitation maximum (Ex Max) at 557-nm and an emission maximum (Em Max) at 610-nm as measured using an antibody-dye conjugate. Driven by BD® innovation, RY610 can be used on both spectral and conventional cytometers and is designed to be excited by the Yellow-Green laser (561-nm) with minimal excitation by the 488-nm blue laser. For conventional instruments equipped with a Yellow-Green laser (561-nm), RY610 can be used as an alternative to PE-CF594 and we recommend using an optical filter centered near 610-nm (eg, a 610/20-nm bandpass filter). For spectral instruments equipped with a Yellow-Green laser (561-nm), it can be used in conjunction with PE-CF594. 格式:RY610最多激发源:557 nm最多发射源:610 nm
保存与运输
建议 2-8℃ 避光保存，请勿冷冻，避免反复冻融。 存储缓冲液：Aqueous buffered solution containing ≤0.09% sodium azide.
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107 的 PBMC 细胞用 100μl 的 Buffer 稀释（Buffer CI：含 0.5% BSA 的 PBS 缓冲液，1 mM EDTA） · 加入多种生物素化抗体，室温下孵育 5 分钟。生物素化的抗体包含以下几种，每种抗体 0.5 μg：CD235a (erythrocytes), CD14 (monocytes), CD3 (T cells), CD15 (granulocytes), CD19 (B cells), CD36 (thrombocytes), CD123
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