产品封面图

Recombinant Human Killer Cell

Immunoglobulin-Like Receptor, 2 Domains Long Cytoplasmic Tail 1
收藏
  • ¥987 - 2457
  • Absin已认证
  • 上海
  • abs44074383
  • 2025年08月28日
    avatar
  • 企业认证

    点击 QQ 联系

    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

    • 保质期

      见优宁维官网

    • 英文名

      Recombinant Human Killer Cell Immunoglobulin-Like Receptor, 2 Domains Long Cytoplasmic Tail 1

    • 库存

      999

    • 供应商

      Absin

    • 规格

      20ug/5ug

    规格:20ug产品价格:¥2457.0
    规格:5ug产品价格:¥987.0

    产品名:

    Recombinant Human Killer Cell Immunoglobulin-Like Receptor, 2 Domains Long Cytoplasmic Tail 1

    品牌:

    Absin

    货号:

    abs44074383

    保持条件:

    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

    浓度:

    见优宁维官网

    免疫原:

    见优宁维官网

    抗原名称:

    见优宁维官网

    应用:

    见优宁维官网

    使用方法:

    见优宁维官网

    产品描述:

        Killer-cell immunoglobulin-like receptors (KIRs), are a family of cell surface glycoproteins found on Natural Killer (NK) Cells, which are important cells of the immune system. They control the killing function of these cells by interacting with MHC class I molecules, which are expressed on all cell types. This interaction allows them to identify virally infected cells or tumor cells that have a distinctive low level of Class I MHC on their surface. The majority of KIRs are inhibitory, which means that their recognition of MHC suppresses the cytotoxic activity of their NK cell. Only a limited number of KIRs have the capacity to activate cells. 
    The KIR genes are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). KIR molecules are extremely polymorphic, meaning their gene sequences differ significantly between individuals, so that different individuals have different arrays/repertoires of KIR genes.
    The KIR proteins are categorized by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM). Whereas KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. 
    KIR2DL1 is an inhibitory Killer Cell Ig-like Receptor (KIR, previously called p58 KIR, p58.1, cl-42, NKAT1, or KIR-K6), which recognizes class I MHC molecules (HLA-Cw2, -Cw4, -Cw5, and Cw6). The extracellular domain of KIR2DL1 was over expressed as insoluble protein aggregates (inclusion bodies).
     
        KIR2DL1 Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing amino acids 1-202 and having a molecular mass of 22.2 kDa.
        The KIR2DL1 is purified by proprietary chromatographic techniques.

    爱必信品牌介绍:

    爱必信(上海)生物科技有限公司是一家从事生物学试剂及耗材的高新技术企业。公司秉承“为生命科学创造便利!为客户创造价值!为员工创造幸福人生!”的发展理念,拥有专业的产品研发质检团队、市场营销团队及先进仓储物流等管理团队。荣获2021年度上海市“专精特新”企业称号。

    自营品牌Absin®,主要经营产品有:生化试剂(常用生化试剂、生物学实验常用试剂、荧光染料、激动剂/抑制剂,植物提取物)、细胞生物学(细胞培养产品、血清、基质胶、添加剂、检测试剂盒)、免疫学产品、分子生物学产品、实验室仪器/耗材、产品定制和检测服务。

    Absin还提供一些独有的特色产品:霍乱毒素B亚单位(CTB)、 鸡胚提取物(CEE)、 牛脑垂体提取物、 呼吸爆发试剂盒、 多色免疫组化试剂盒、 mRNA原料等在业界深受客户喜欢。

    Absin秉承踏实,务实,求精和不断创新的精神为中国科学家提供优质产品,努力打造属于中国自己的生物试剂品牌,为广大科学家提供更全面更丰富更优质的产品。

    产品细节图片1

    更多商品信息请了解优宁维官网>>

    风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标文献和实验
    相关实验
    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    ¥987
    爱必信(上海)生物科技有限公司
    2025年09月23日询价
    ¥987
    上海优宁维生物科技股份有限公司
    2025年08月28日询价
    询价
    默瑞(上海)生物科技有限公司
    2025年07月11日询价
    ¥4729
    上海北诺生物科技有限公司
    2025年05月25日询价
    Recombinant Human Killer Cell Immunoglobulin-Like Receptor, 2 Domains Long Cytoplasmic Tail 1
    ¥987 - 2457