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Recombinant Human Factor VIIa

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  • ¥2499 - 6783
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  • 上海
  • abs44074300
  • 2025年08月28日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      Lyophilized Factor-VIIa although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Factor-VIIa should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.

    • 保质期

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    • 英文名

      Recombinant Human Factor VIIa

    • 库存

      999

    • 供应商

      Absin

    • 规格

      50ug/10ug

    规格:50ug产品价格:¥6783.0
    规格:10ug产品价格:¥2499.0

    产品名:

    Recombinant Human Factor VIIa

    品牌:

    Absin

    货号:

    abs44074300

    保持条件:

    Lyophilized Factor-VIIa although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Factor-VIIa should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.

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    产品描述:

         Coagulation factor VII is a vitamin K-dependent factor which is essential for hemostasis. It circulates in the blood as a zymogen which is later converted to an active form by factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of factor VII, a heavy chain with a catalytic domain and a light chain with 2 EGF-like domains are generated, and the two chains are held together by a disulfide bond. The presence of factor III and calcium ions further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Alternative splicing of factor VII results in 2 transcripts. Defects in coagulation factor VII can cause coagulopathy. Coagulation factor VII initiates the extrinsic pathway of blood coagulation. Minor proteolysis converts factor VII to factor VIIa by factors Xa, XIIa, IXa, or thrombin. Factor VIIa also converts factor IX to factor IXa in the presence of tissue factor and calcium.

        Factor VIIa Human Recombinant produced in BHK is a glycosylated polypeptide two-chain dimer consisting of 406 amino acids with a molecular weight of 50kD.The Factor-VIIa is purified by proprietary chromatographic techniques.
        SOURCE:BHK cells (Baby Hamster Kidney Cells).

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    图标文献和实验
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