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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
- 保质期:
见优宁维官网
- 英文名:
SIRT1/2 Inhibitor IV, Cambinol
- 库存:
999
- 供应商:
Absin
- 规格:
10mg/5mg
| 规格: | 10mg | 产品价格: | ¥1742.0 |
|---|---|---|---|
| 规格: | 5mg | 产品价格: | ¥970.0 |
产品名:
SIRT1/2 Inhibitor IV, Cambinol品牌:
Absin货号:
abs819402保持条件:
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.浓度:
见优宁维官网免疫原:
见优宁维官网抗原名称:
SIRT1,SIRT2应用:
An inhibitor of SIRT1, SIRT2, and SIRT5使用方法:
other产品描述:
SIRT1/2 Inhibitor IV, Cambinol is a cell-permeable b-naphthol compound that inhibits the NAD-dependent deacetylase activity of SIRT1 and SIRT2 (IC50 = 56 μM and 59 μM, respectively) in a substrate-, but not NAD-, competitive manner. SIRT1/2 Inhibitor IV, Cambinol inhibits SIRT5 deacetylase activity only at much higher concentrations (IC50 >300 μM) and exhibits no inhibition against class I and II HDACs. Cambinol-induced apoptosis in BCL6-expressing Burkitt lymphoma cell lines has been attributed to the hyperacetylation of BCL6 and p53.
爱必信品牌介绍:
爱必信(上海)生物科技有限公司是一家从事生物学试剂及耗材的高新技术企业。公司秉承“为生命科学创造便利!为客户创造价值!为员工创造幸福人生!”的发展理念,拥有专业的产品研发质检团队、市场营销团队及先进仓储物流等管理团队。荣获2021年度上海市“专精特新”企业称号。
自营品牌Absin®,主要经营产品有:生化试剂(常用生化试剂、生物学实验常用试剂、荧光染料、激动剂/抑制剂,植物提取物)、细胞生物学(细胞培养产品、血清、基质胶、添加剂、检测试剂盒)、免疫学产品、分子生物学产品、实验室仪器/耗材、产品定制和检测服务。
Absin还提供一些独有的特色产品:霍乱毒素B亚单位(CTB)、 鸡胚提取物(CEE)、 牛脑垂体提取物、 呼吸爆发试剂盒、 多色免疫组化试剂盒、 mRNA原料等在业界深受客户喜欢。
Absin秉承踏实,务实,求精和不断创新的精神为中国科学家提供优质产品,努力打造属于中国自己的生物试剂品牌,为广大科学家提供更全面更丰富更优质的产品。

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文献和实验Methods to Assay Inhibitors of DNA Gyrase and Topoisomerase IV Activities
on DNA supercoiling by S. pneumoniae gyrase, DNA decatenation by S. pneumoniae topo IV, and DNA cleavage by both enzymes. These approaches provide mechanistic insight on inhibitor action and allow identification of dual gyrase/topo IV targeting agents
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