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APC anti-mouse CD93 (AA4.1, ea

rly B lineage)
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  • ¥2509.14
  • BioLegend
  • 136510
  • 美国
  • 2025年08月24日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 抗体名

      APC anti-mouse CD93 (AA4.1, early B lineage)

    • 抗体英文名

      APC anti-mouse CD93 (AA4.1, early B lineage)

    • 供应商

      上海善然生物科技有限公司

    • 保存条件

      2-8℃

    • 规格

      100ug

    APC anti-mouse CD93 (AA4.1, early B lineage) Antibody
    AA4.1
    Catalog# / Size 
    136510 / 100 µg
    Clone
    Regulatory Status RUO
    Other Names AA4.1, C1qRp, Early B lineage antigen
    Isotype Rat IgG2b, κ
    Description CD93 is a 130-140kD C-type lectin like type I transmembrane protein, also known as complement
    component 1, q subcomponent (C1qR1), C1qRp collectin receptor (C1qRp), or AA4 antigen. It is a
    receptor expressed on immature B lymphocytes, hematopoietic progenitors and stem cells in adult
    bone marrow, fetal liver, embryonic yolk sac. CD93 expression level on splenic
    immature/transitional B cells is much lower than in bone marrow. It is reinduced during plasma cell
    differentiation and plays an important role in maintaining plasma cells in bone marrow niches.
    Immature dendritic cells express CD93 and down-regulate this molecule upon maturation,
    suggesting a role in uptake of particles by DC. It is also expressed on monocytes, macrophages,
    and endothelial cells. Macrophages from CD93 (-/-) mice had a significant phagocytic defect in the
    clearance of apoptotic cells in vivo, indicating CD93 may contribute to the in vivo clearance of
    dying cells. Binding of CD93 to C1q remains controversial.

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    图标文献和实验
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