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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
APC anti-mouse CD93 (AA4.1, early B lineage)
- 抗体英文名:
APC anti-mouse CD93 (AA4.1, early B lineage)
- 供应商:
上海善然生物科技有限公司
- 保存条件:
2-8℃
- 规格:
100ug
APC anti-mouse CD93 (AA4.1, early B lineage) Antibody
AA4.1
Catalog# / Size
136510 / 100 µg
Clone
Regulatory Status RUO
Other Names AA4.1, C1qRp, Early B lineage antigen
Isotype Rat IgG2b, κ
Description CD93 is a 130-140kD C-type lectin like type I transmembrane protein, also known as complement
component 1, q subcomponent (C1qR1), C1qRp collectin receptor (C1qRp), or AA4 antigen. It is a
receptor expressed on immature B lymphocytes, hematopoietic progenitors and stem cells in adult
bone marrow, fetal liver, embryonic yolk sac. CD93 expression level on splenic
immature/transitional B cells is much lower than in bone marrow. It is reinduced during plasma cell
differentiation and plays an important role in maintaining plasma cells in bone marrow niches.
Immature dendritic cells express CD93 and down-regulate this molecule upon maturation,
suggesting a role in uptake of particles by DC. It is also expressed on monocytes, macrophages,
and endothelial cells. Macrophages from CD93 (-/-) mice had a significant phagocytic defect in the
clearance of apoptotic cells in vivo, indicating CD93 may contribute to the in vivo clearance of
dying cells. Binding of CD93 to C1q remains controversial.
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文献和实验Fate-mapping and lineage-tracing studies that were performed on mouse embryos maintained in culture have provided a unique insight into the morphogenetic processes that take place during gastrulation and early organogenesis. These experiments
图2 APC 5'末端的扩增。用对应APC mRNA的位置5846的GSP反转录1mg Hela总RNA得到APC mRNA。cDNA被纯化、加尾,和用对应位置1797(A带)和位置1632(B带)的引物和AAP一起,用ELONGASE酶混合物来扩增(94℃ 30s,接着35个循环的94℃ 15 s,55℃ 30 s,68℃ 5 min)。初步PCR用TE缓冲液稀释100倍,取1ml用引物APC-1632(A带)或引物APC-1242(B带)和AUAP分别重新扩增(30个循环),每个PCR
Early development of primary motor neurons and somites in Zebrafish Embryos
boundaries. The ZNP-1 and F6 treated embryos will be treated with a secondary antibody, Fluorescent Goat anti-mouse IgG, so that the stained neurons and somites can be observed under a fluorescent microscope. Procedure: 1. Dechorionate 24
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