- ￥1700 - 2850
- Solarbio|ActivAb
- 北京
- K011457P
- 2025年08月22日
- WB;IHC;IF
- Rabbit
- Rat;Mouse
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
A synthetic peptide of human RAGE
- 亚型：
IgG
- 保存条件：
Store at -20℃.Avoid freeze/thaw cycles.
- 克隆性：
Polyclonal Antibody
- 标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
- 适应物种：
Rat;Mouse
- 抗原来源：
A synthetic peptide of human RAGE
- 目录编号：
177
- 级别：
实验级别
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
WB;IHC;IF
- 浓度：
WB 1:500-2000. IHC 1:100-500. IF 1:100-500.
- 靶点：
RAGE
- 抗体英文名：
Anti-RAGE Polyclonal Antibody
- 抗体名：
晚期糖基化终末产物特异性受体抗体
- 规格：
100ul/50ul
| 规格： | 100ul | 产品价格： | ￥2850.0 |
|---|---|---|---|
| 规格： | 50ul | 产品价格： | ￥1700.0 |
| 基本信息 | |
| 英文名称 | Anti-RAGE Polyclonal Antibody |
| 中文名称 | 晚期糖基化终末产物特异性受体抗体 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Rat;Mouse |
| 预测交叉反应 | Human;Pig;Cow;Dog |
| 应用 | WB;IHC;IF |
| 稀释比例 | WB 1:500-2000. IHC 1:100-500. IF 1:100-500. |
| 密度 | |
| 靶标 | RAGE |
| 别名 | Advanced glycosylation end product specific receptor;Advanced glycosylation end product-specific receptor;AGER;EC 2.7.11.22;LE 9211 A antigen;LE-9211-A antigen;MGC22357;MOK;RAGE 1;RAGE1;MOK protein kinase;Receptor for advanced glycation endproducts;Renal tumor antigen 1;Renal tumor antigen;Renal cell carcinoma antigen (MOK protein kinase);Renal tumor antigen 1;RAGE_HUMAN. |
| 背景说明 | Advanced glycosylation end product-specific receptor (AGER;RAGE) is a member of the immunoglobulin superfamily of cell surface molecules that binds molecules that have been irreversibly modified by non-enzymatic glycation and oxidation and are know as advanced glycation end products (AGEs).It is expressed by endothelium mononuclear phagocytes neurons and smooth muscle cells.Whereas RAGE is present at high levels during development especially in the central nervous system its levels decline during maturity.The increased expression of RAGE is associated with several pathological states such as diabetic vasculopathy neuropathy retinopathy and other disorders including Alzheimer’s disease and immune/inflammatory reactions of the vessel walls.In diabetic tissues the production of RAGE is due to the overproduction of AGEs that eventually overwhelm the protective properties of RAGE.This results in oxidative stress and endothelial cell dysfunction that leads to vascular disease in diabetics.In the brain RAGE also binds amyloid beta (Ab).Because Ab is overproduced in neurons and vessels in the brains of Alzheimer disease this leads to the hyperstimulation of RAGE.The RAGE-Ab interaction is thought to result in oxidative stress leading to neuronal degeneration. |
| Swiss Prot | Q15109 |
| Gene ID | 177 |
| 亚细胞定位 | Cell membrane Single-pass type I membrane proteinSecreted |
| 免疫原 | A synthetic peptide of human RAGE |
| Public Immunogen Range | 41-150/404aa |
| 理论分子量 | 13/35/36/37/38/39/41/43/45kDa |
| 实际分子量 | 58/50kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | 0.01M TBS(pH7.4) with 1% BSA，0.03% Proclin300 and 50% Glycerol. |
| 储存条件 | Store at -20℃.Avoid freeze/thaw cycles. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
a simple ELISA method to detect human anti-antibody response.
技术资料暂无技术资料 索取技术资料
