- ￥480 - 1600
- Solarbio|ActivAb
- 北京
- K115916P
- 2025年08月22日
- WB;IHC
- Rabbit
- Human;Mouse
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant protein of human EXD2
- 亚型：
IgG
- 保存条件：
Store at -20℃. Avoid freeze / thaw cycles.
- 克隆性：
Polyclonal Antibody
- 标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
- 适应物种：
Human;Mouse
- 抗原来源：
Recombinant protein of human EXD2
- 目录编号：
55218
- 级别：
实验级别
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
WB;IHC
- 浓度：
WB 1:1000-3000.IHC 1:50-200.
- 靶点：
EXD2
- 抗体英文名：
Anti-EXD2 Polyclonal Antibody
- 抗体名：
核酸外切酶3’-5’结构域样2
- 规格：
20ul/100ul/50ul
| 规格： | 20ul | 产品价格： | ￥480.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 规格： | 50ul | 产品价格： | ￥960.0 |
| 基本信息 | |
| 英文名称 | Anti-EXD2 Polyclonal Antibody |
| 中文名称 | 核酸外切酶3’-5’结构域样2 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Human;Mouse |
| 应用 | WB;IHC |
| 稀释比例 | WB 1:1000-3000.IHC 1:50-200. |
| 密度 | |
| 靶标 | EXD2 |
| 别名 | Exonuclease 3’-5’ domain-containing protein 2;EC:3.1.11.1;3’-5’ exoribonuclease EXD2;EC:3.1.13.-;EC:3.1.13.-;Exonuclease 3’-5’ domain-like-containing protein 2;C14orf114;EXDL2; |
| 背景说明 | Exonuclease that has both 3’-5’ exoribonuclease and exodeoxyribonuclease activities， depending on the divalent metal cation used as cofactor (PubMed:29335528， PubMed:31127291).In presence of Mg2+， only shows 3’-5’ exoribonuclease activity， while it shows both exoribonuclease and exodeoxyribonuclease activities in presence of Mn2+ (PubMed:29335528， PubMed:31127291).Acts as an exoribonuclease in mitochondrion， possibly by regulating ATP production and mitochondrial translation (PubMed:29335528).Also involved in the response to DNA damage (PubMed:26807646， PubMed:31255466).Acts as 3’-5’ exodeoxyribonuclease for double-strand breaks resection and efficient homologous recombination (PubMed:20603073， PubMed:26807646).Plays a key role in controlling the initial steps of chromosomal break repair， it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3’-5’ exonuclease activity， which efficiently processes double-stranded DNA substrates containing nicks (PubMed:26807646).Also involved in response to replicative stress: recruited to stalled forks and is required to stabilize and restart stalled replication forks by restraining excessive fork regression， thereby suppressing their degradation (PubMed:31255466). |
| Swiss Prot | Q9NVH0 |
| Gene ID | 55218 |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | Recombinant protein of human EXD2 |
| Public Immunogen Range | 101-400aa |
| 理论分子量 | 56/70kDa |
| 实际分子量 | 66kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | PBS with 50% Glycerol， 0.03% Proclin300， 0.5% BSA， pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze / thaw cycles. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
a simple ELISA method to detect human anti-antibody response.
技术资料暂无技术资料 索取技术资料
