- ￥480 - 1600
- Solarbio|ActivAb
- 北京
- K116497P
- 2025年08月22日
- WB;IHC
- Rabbit
- Human;Mouse;Rat
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- 详细信息
- 技术资料
- 免疫原：
A synthetic peptide of human SMAD2
- 亚型：
IgG
- 保存条件：
Store at -20℃. Avoid freeze / thaw cycles.
- 标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
- 适应物种：
Human;Mouse;Rat
- 抗原来源：
A synthetic peptide of human SMAD2
- 目录编号：
4087
- 级别：
实验级别
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
WB;IHC
- 浓度：
WB 1:1000-3000. IHC 1:50-200.
- 靶点：
SMAD2
- 抗体英文名：
Anti-SMAD2 Polyclonal Antibody
- 抗体名：
细胞信号转导分子Smad-2抗体
- 规格：
50ul/20ul/100ul
| 规格： | 50ul | 产品价格： | ￥960.0 |
|---|---|---|---|
| 规格： | 20ul | 产品价格： | ￥480.0 |
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 基本信息 | |
| 英文名称 | Anti-SMAD2 Polyclonal Antibody |
| 中文名称 | 细胞信号转导分子Smad-2抗体 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Human;Mouse;Rat |
| 预测交叉反应 | Cow(100%);Chicken(84.6%);Pig(84.6%);Chimpanzee(100%);Zebrafish(100%) |
| 应用 | WB;IHC |
| 稀释比例 | WB 1:1000-3000. IHC 1:50-200. |
| 密度 | |
| 靶标 | SMAD2 |
| 别名 | DKFZP586N0721; DKFZp686J10186; hMAD 3; hMAD-3; hSMAD3; HSPC193; HST17436; JV15 2; JV15-2; JV152; LDS1C; LDS3; MAD (mothers against decapentaplegic Drosophila) homolog 3; MAD homolog 3; Mad homolog JV15 2; Mad protein homolog; MAD， mothers against decapentaplegic homolog 3; Mad3; MADH 3; MADH3; MGC60396; Mothers against decapentaplegic homolog 3; Mothers against DPP homolog 3; SMA and MAD related protein 3; SMAD 3; SMAD; SMAD family member 3; SMAD， mothers against DPP homolog 3; Smad3; SMAD3_HUMAN; Drosophila， homolog of， MADR2; hMAD-2; HsMAD2; JV18; JV18-1; JV181; MAD; MAD homolog 2; MAD Related Protein 2; Mad-related protein 2; MADH2; MADR2; MGC22139; MGC34440; Mother against DPP homolog 2; Mothers against decapentaplegic homolog 2; Mothers against decapentaplegic， Drosophila， homolog of， 2; Mothers against DPP homolog 2; OTTHUMP00000163489; Sma and Mad related protein 2; Sma- and Mad-related protein 2 MAD; SMAD 2; SMAD family member 2; SMAD， mothers against DPP homolog 2; SMAD2; SMAD2_HUMAN; |
| 背景说明 | The protein encoded by this gene belongs to the SMAD， a family of proteins similar to the gene products of the Drosophila gene ‘mothers against decapentaplegic‘ (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta， and thus regulates multiple cellular processes， such as cell proliferation， apoptosis， and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal， this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus， where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase， and mediates the signal from the activin. Alternatively spliced transcript variants have been observed for this gene. |
| Swiss Prot | Q15796 |
| Gene ID | 4087 |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | A synthetic peptide of human SMAD2 |
| Public Immunogen Range | 417-467/467aa |
| 理论分子量 | 49/52kDa |
| 实际分子量 | 63kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | PBS with 50% Glycerol， 0.03% Proclin300， 0.5% BSA， pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze / thaw cycles. |
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K116497P Anti-SMAD2 Polyclonal Antibody
￥480 - 1600
