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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
A synthetic peptide of human Caspase-1 P10
- 亚型:
IgG
- 保存条件:
Store at -20℃. Avoid freeze / thaw cycles.
- 克隆性:
Polyclonal Antibody
- 标记物:
Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,Solar Fluor 350,Solar Fluor 405,Solar Fluor 488,Solar Fluor 532,Solar Fluor 555,Solar Fluor 568,Solar Fluor 594,Solar Fluor 633,Solar Fluor 640,Solar Fluor 647,Solar Fluor 660,Solar Fluor 680,Solar Fluor 750
- 适应物种:
Human;Mouse
- 抗原来源:
A synthetic peptide of human Caspase-1 P10
- 目录编号:
834
- 级别:
实验级别
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 宿主:
Rabbit
- 应用范围:
WB;FCM
- 浓度:
WB 1:500-2000. FCM 1ug/Test.
- 靶点:
Caspase-1 P10
- 抗体英文名:
Anti-Caspase-1 P10 Polyclonal Antibody
- 抗体名:
天冬氨酸-胱氨酸特异性蛋白酶家族抗体
- 规格:
50ul/100ul
| 规格: | 50ul | 产品价格: | ¥1700.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥2850.0 |
| 基本信息 | |
| 英文名称 | Anti-Caspase-1 P10 Polyclonal Antibody |
| 中文名称 | 天冬氨酸-胱氨酸特异性蛋白酶家族抗体 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Human;Mouse |
| 应用 | WB;FCM |
| 稀释比例 | WB 1:500-2000. FCM 1ug/Test. |
| 密度 | |
| 靶标 | Caspase-1 P10 |
| 别名 | caspase-1 isoform alpha p10 subunit; CASP 1; CASP1; Caspase 1 apoptosis related cysteine peptidase; Caspase 1 apoptosis related cysteine protease; Caspase1; ICE; IL 1 beta converting enzyme; IL 1BC; IL1B convertase; IL1BC; IL1BCE; Interleukin 1 beta convertase; Interleukin 1 beta convertase precursor; Interleukin 1 beta converting enzyme. CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45; Caspase-1 subunit p10 |
| 背景说明 | Thiol protease involved in a variety of inflammatory processes by proteolytically cleaving other proteins, such as the precursors of the inflammatory cytokines interleukin-1 beta (IL1B) and interleukin 18 (IL18) as well as the pyroptosis inducer Gasdermin-D (GSDMD), into active mature peptides (PubMed:15326478, PubMed:15498465, PubMed:1574116, PubMed:26375003, PubMed:32051255, PubMed:37993714, PubMed:7876192, PubMed:9334240). Plays a key role in cell immunity as an inflammatory response initiator: once activated through formation of an inflammasome complex, it initiates a pro-inflammatory response through the cleavage of the two inflammatory cytokines IL1B and IL18, releasing the mature cytokines which are involved in a variety of inflammatory processes (PubMed:15326478, PubMed:15498465, PubMed:1574116, PubMed:32051255, PubMed:7876192). |
| Swiss Prot | P29466 |
| Gene ID | 834 |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | A synthetic peptide of human Caspase-1 P10 |
| Public Immunogen Range | 321-404aa |
| 理论分子量 | 10/30/35/43/45kDa |
| 实际分子量 | 45kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 储存条件 | Store at -20℃. Avoid freeze / thaw cycles. |
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文献和实验. A rabbit polyclonal antisera is also available (101c500; BAbCO) but in our hands this was less reactive. The antibody cleanup protocol is now a seperate document Protocol Cells are grown in 5 mls of YPAD to an O.D. 600 of 0.75 to 1.
suspended in PBS. A rabbit polyclonal antisera is also available (101c500; BAbCO) but in our hands this was less reactive. The antibody cleanup protocol is now a seperate document Protocol Cells are grown in 5 mls of YPAD to an O.D. 600
make an Antibody against a Peptides
Carriers Figure 2. EDC-Mediated Peptide-Carrier Conjugation 上一篇:Purification Of Anti Peptide Antibody 下一篇:Polyclonal Antibody Production
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