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- 详细信息
- 文献和实验
- 技术资料
- 亚型:
IgG1
- 保存条件:
Store at 4℃ in dark.Do not freeze.
- 克隆性:
Monoclonal Antibody
- 标记物:
Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,Solar Fluor 350,Solar Fluor 405,Solar Fluor 488,Solar Fluor 532,Solar Fluor 555,Solar Fluor 568,Solar Fluor 594,Solar Fluor 633,Solar Fluor 640,Solar Fluor 647,Solar Fluor 660,Solar Fluor 680,Solar Fluor 750
- 适应物种:
Human
- 目录编号:
962
- 级别:
实验级别
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 宿主:
Mouse
- 应用范围:
FCM
- 靶点:
CD48
- 抗体英文名:
Anti-CD48 Monoclonal Antibody
- 抗体名:
BLAST,BLAST1,CD48,CD48 antigen,CD48 molecule,hCD48,Leukocyte antigen MEM 102,mCD48,MEM 102,SLAMF2,TCT.1
- 规格:
100ug/1mg
| 规格: | 100ug | 产品价格: | ¥800.0 |
|---|---|---|---|
| 规格: | 1mg | 产品价格: | ¥3250.0 |
| 基本信息 | |
| 英文名称 | Anti-CD48 Monoclonal Antibody |
| 宿主 | Mouse |
| 克隆类型 | Monoclonal Antibody |
| 亚型 | IgG1 |
| 交叉反应 | Human |
| 应用 | FCM |
| 密度 | |
| 靶标 | CD48 |
| 别名 | BLAST,BLAST1,CD48,CD48 antigen,CD48 molecule,hCD48,Leukocyte antigen MEM 102,mCD48,MEM 102,SLAMF2,TCT.1 |
| 背景说明 | Glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that interacts via its N-terminal immunoglobulin domain with cell surface receptors including 2B4/CD244 or CD2 to regulate immune cell function and activation (PubMed:27249817,PubMed:12007789).Participates in T-cell signaling transduction by associating with CD2 and efficiently bringing the Src family protein kinase LCK and LAT to the TCR/CD3 complex (PubMed:19494291).In turn,promotes LCK phosphorylation and subsequent activation (PubMed:12007789).Induces the phosphorylation of the cytoplasmic immunoreceptortyrosine switch motifs (ITSMs) of CD244 initiating a series of signaling events that leads to the generation of the immunological synapse and the directed release of cytolytic granules containing perforin and granzymes by T-lymphocytes and NK-cells (PubMed:9841922,PubMed:27249817). |
| Swiss Prot | P09326 |
| Gene ID | 962 |
| 亚细胞定位 | Cell membrane |
| 储存条件 | Store at 4℃ in dark.Do not freeze. |
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文献和实验指仅对一种抗原决定基的纯粹的抗体。这类抗体不可能通过将抗原 胞的 Hybridoma,在试管内制成了纯粹的单克隆抗体。用某种抗原使动物产生免疫感应,对应于抗原之不同部分可制成各种不同的抗体复合体。然而,因为一个产生抗体的细胞,只能产生一种抗体,所以骨髓肿瘤细胞与产生抗体细胞间的细胞杂种,可形成边产生抗体边增殖的 hybridoma,将每个杂种细胞进行克隆(无性繁殖系)培养,则一个克隆的细胞群只由单种类产生同一抗体的细胞所组成,这样得到的就是单克隆抗体。此抗体在测定
Monoclonal Antibody Production
Order 6 six week old Balb/C mice and let the ARC know they are coming.Have your antigen ready for when they arrive.Once they get there earmark the mice and perform a pre-bleed on them to be used as an ELISA control for monitoring the titer
a simple ELISA method to detect human anti-antibody response.
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