- ￥480 - 1600
- Solarbio|ActivAb
- 北京
- K115159P
- 2025年08月22日
- IHC
- Rabbit
- Human;Mouse;Rat
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant protein of human PTEN
- 亚型：
IgG
- 保存条件：
Store at -20℃. Avoid freeze / thaw cycles.
- 克隆性：
Polyclonal Antibody
- 标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
- 适应物种：
Human;Mouse;Rat
- 抗原来源：
Recombinant protein of human PTEN
- 目录编号：
5728
- 级别：
实验级别
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
IHC
- 浓度：
IHC 1:50-200.
- 靶点：
PTEN
- 抗体英文名：
Anti-PTEN Polyclonal Antibody
- 抗体名：
同源性磷酸酶-张力蛋白
- 规格：
20ul/100ul/50ul
| 规格： | 20ul | 产品价格： | ￥480.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 规格： | 50ul | 产品价格： | ￥960.0 |
| 基本信息 | |
| 英文名称 | Anti-PTEN Polyclonal Antibody |
| 中文名称 | 同源性磷酸酶-张力蛋白 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Mouse;Human |
| 预测交叉反应 | Dog |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-200. |
| 密度 | |
| 靶标 | PTEN |
| 别名 | 10q23del;BZS;DEC;GLM2;MGC11227;MHAM;MMAC1;MMAC1 phosphatase and tensin homolog deleted on chromosome 10;Mutated in multiple advanced cancers 1;Phosphatase and tensin homolog;Phosphatase and tensin like protein;Phosphatidylinositol 3，4，5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN;Pten;PTEN_HUMAN;PTEN1;TEP1; |
| 背景说明 | This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol-3，4，5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases，this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3，4，5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway. The use of a non-canonical (CUG) upstream initiation site produces a longer isoform that initiates translation with a leucine，and is thought to be preferentially associated with the mitochondrial inner membrane. This longer isoform may help regulate energy metabolism in the mitochondria. A pseudogene of this gene is found on chromosome 9. Alternative splicing and the use of multiple translation start codons results in multiple transcript variants encoding different isoforms. [provided by RefSeq，Feb 2015] |
| Swiss Prot | P60484 |
| Gene ID | 5728 |
| 亚细胞定位 | Cytoplasm Cell membrane |
| 免疫原 | Recombinant protein of human PTEN |
| Public Immunogen Range | 1-403aa |
| 理论分子量 | 18/47/65kDa |
| EC | |
| 纯化方法 | Octanoic acid-ammonium sulfate precipitation |
| 储存液 | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze / thaw cycles. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
a simple ELISA method to detect human anti-antibody response.
技术资料暂无技术资料 索取技术资料
