- ￥480 - 1600
- Solarbio|ActivAb
- 北京
- K115058P
- 2025年08月22日
- IHC
- Rabbit
- Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant protein of human HLA-A
- 亚型：
IgG
- 保存条件：
Store at -20℃. Avoid freeze / thaw cycles.
- 克隆性：
Polyclonal Antibody
- 标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
- 适应物种：
Mouse
- 抗原来源：
Recombinant protein of human HLA-A
- 目录编号：
3105
- 级别：
实验级别
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
IHC
- 浓度：
IHC 1:25-100.
- 靶点：
HLA-A
- 抗体英文名：
Anti-HLA-A Polyclonal Antibody
- 抗体名：
主要组织相容性复合体I类A
- 规格：
20ul/100ul/50ul
| 规格： | 20ul | 产品价格： | ￥480.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 规格： | 50ul | 产品价格： | ￥960.0 |
| 基本信息 | |
| 英文名称 | Anti-HLA-A Polyclonal Antibody |
| 中文名称 | 主要组织相容性复合体I类A |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Mouse |
| 应用 | IHC |
| 稀释比例 | IHC 1:25-100. |
| 密度 | |
| 靶标 | HLA-A |
| 别名 | Histocompatibility antigen; HLA A; HLA class I histocompatibility antigen A 3 alpha chain; HLA class I histocompatibility antigen A3 alpha chain; HLAA; MHC class I antigen A*3; MHC class I antigen A3; |
| 背景说明 | HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen so that they can be recognized by cytotoxic T cells. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide; exons 2 and 3 encode the alpha1 and alpha2 domains; which both bind the peptide; exon 4 encodes the alpha3 domain; exon 5 encodes the transmembrane region; and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. More than 6 HLA-A alleles have been described. The HLA system plays an important role in the occurrence and outcome of infectious diseases; including those caused by the malaria parasite; the human immunodeficiency virus (HIV); and the severe acute respiratory syndrome coronavirus (SARS-CoV). The structural spike and the nucleocapsid proteins of the novel coronavirus SARS-CoV-2; which causes coronavirus disease 219 (COVID-19); are reported to contain multiple Class I epitopes with predicted HLA restrictions. Individual HLA genetic variation may help explain different immune responses to a virus across a population. |
| Swiss Prot | P04439 |
| Gene ID | 3105 |
| 亚细胞定位 | Cell membrane Secreted Cytoplasm |
| 免疫原 | Recombinant protein of human HLA-A |
| Public Immunogen Range | 40-300aa |
| 理论分子量 | 41kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze / thaw cycles. |
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文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
a simple ELISA method to detect human anti-antibody response.
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