Rabbit anti-TrkB Recombinant M

别名：兔抗TrkB重组单克隆抗体(S-488-5)

免疫原：Recombinant Protein

应用：WB: 1:1000, IHC-P: 1:500

保持条件：Store at -20℃ for one year.

使用方法：WB,IHC-P

标记：Unlabeled

宿主：Rabbit

反应种属：见优宁维官网

克隆性：S-488-5

产品描述：

Neurotrophins function to regulate naturally occurring cell death of neurons during development. The prototype neurotrophin is nerve growth factor (NGF), originally discovered in the 1950s as a soluble peptide promoting the survival of, and neurite outgrowth from, sympathetic ganglia. Three additional structurally homologous neurotrophic factors have been identified. These include brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3) and neurotrophin-4 (NT-4) (also designated NT-5). These various neurotrophins stimulate the in vitro survival of distinct, but partially overlapping, populations of neurons. The cell surface receptors through which neurotrophins mediate their activity have been identified. For instance, the Trk A receptor is the preferential receptor for NGF, but also binds NT-3 and NT-4. The Trk B receptor binds both BDNF and NT-4 equally well, and binds NT-3 to a lesser extent, while the Trk C receptor only binds NT-3.

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