Rabbit anti-WT1 Recombinant Mo

别名：兔抗WT1重组单克隆抗体(R076)

免疫原：见优宁维官网

应用：WB: 1:2000, IHC-P: 1:250-1:500, ICC: 1:500, FCM(Intra): 1:500

保持条件：Store at -20℃ for one year.

使用方法：WB,IHC-P,ICC,FlowCytometry

标记：Unlabeled

宿主：Rabbit

反应种属：见优宁维官网

克隆性：R076

产品描述：

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm‘s tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq, Oct 2010]

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